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Hanson Research Lab

Cellular decoding of inputs gives rise to multiple outputs
Cells integrate and decode diverse inputs to initiate discrete output events using cellular signaling networks


Decoding the principles of cellular signaling networks

Our research focuses on understanding the molecular mechanisms by which cells integrate information from intracellular and extracellular signals and process this information to enact specific cellular programs, for example cell survival or cell death. To explore these questions, we make use of fluorescent biosensors, time-lapse imaging, cellular biology and basic modeling to interrogate how the architecture of these signaling networks encode and decode information through spatiotemporal patterns to regulate cell function.  Importantly, we aim to understand how dysfunction of these networks contributes to human malignancy in the case of cancer.