Office BuildingWagner Hall
Mailing AddressWagner Hall 419
Health & Nutritional Sciences-Box 2275A
Brookings, SD 57007
BiographyDr. Dey directs the molecular nutrition and nutrigenomics research program at SDSU and teaches related courses in undergraduate and graduate level nutrition science classes. Her research investigates the health promoting effects and underlying molecular mechanisms of dietary bioactives using a combination of animal models for human diseases, human subjects, and a genome-science approach. Dr. Dey is frequently invited to serve the nutrition science profession as journal reviewer, editorial board member for journals, invited speaker, grant reviewer (NIH, DoD, FFAR etc.), and beyond. Nearly twenty researchers, including graduate (PhD and MS) and undergraduate students as well as postdoctoral scholars, have received funding, research training at the interface of nutrition and biomedical sciences, and mentoring toward professional development in the Dey lab from 2010–2017. In Dey-lab researchers learn how to perform as high-functioning, collaborative team members, acquire critical and analytical skills, problem-solving proficiency, and an ability to learn quickly and function independently. Researchers interested in a position in Dey-Lab may contact using the email link provided on the top of the page.
Area(s) of ResearchThe long term goal of Dr. Dey’s research, funded by federal, state, and private entities, is to advance nutritional knowledge through a deeper understanding of the molecular interactions of dietary components with the host and the microbiome. Currently, most evidence of nutrient derived health benefits comes from limited research or observational human studies. However, continuous interactions between food and the human body throughout the life's journey are complex, involving multiple organ physiology on all levels of regulation, including genes, proteins, and metabolites. Understanding these interactions, therefore, may unlock the untapped potential of nutrition science to prevent and/or help treat chronic diseases such as in the context of cardio-metabolic disorders and cancers. As chronic diseases continue to be the leading causes of morbidity and mortality worldwide, understanding how nutrition influences our disease risk and well-being will provide science-based precise food awareness to promote positive dietary changes for a healthier society.
Some of the recent research projects in Dey-lab include:
A. Role of Diet in Metabolic Health Promotion
(i) Study of the prebiotic functions of a digestion-resistant starch and its role in promoting cardio-metabolic health,
(ii) Characterization of the changing role of the gut microbiome with age on weight-loss interventions,
(iii) Investigation of the effect of prenatal high-fat diet on the offspring’s cardio-metabolic disease risks through epigenetic programming
B. Anti-inflammatory and Chemopreventive Phytochemicals
(iv) Evaluation of the biological activity of triptolide and oat avenanthramides against inflammation and carcinogenesis
(v) Potential role of a dietary isothiocyanate in inflammatory bowel disease and colon cancer.
Our projects are typically executed in multiple phases over many years. A list of peer-reviewed publications from Dey-lab is available at the NCBI link on this page while news stories may be found through Google search.