… Research Interests - Logue Lab The overarching themes of my research are bioanalytical chemistry, sample preparation and materials/organic chemistry. The bioanalytical research focuses on the detection of chemical and biological … Linked with Extractive Stirrer). Current and future projects include research in CBW agent detection, environmental contaminant analysis, sensor development and the analysis of flavor compounds via ICECLES. Determining past exposure to CBW agents in biological matrices is difficult because the "window of detection" of most chemical agents is very short. In the …
… are in high demand by utilities, hospitals and national laboratories. Students that pursue an internship or an undergraduate research project in an area of nuclear science or nuclear engineering are well-prepared for these opportunities. The ability of materials to perform in high-radiation environments is of interest for nuclear power, space exploration and fusion … isotopes in the environment via gamma spectroscopy and alpha/beta counting. Such isotopes serve as natural radiotracers for natural or man-made activities. Neutron activation analysis complements mass spectroscopy by assaying trace amounts of heavy metals after exposure to neutrons. Construction and calibration of new detectors is also of interest. Dr. McTaggart has … counting for ultra-low levels of Uranium, Thorium and Potassium isotopes that produce unwanted statistical backgrounds for rare event physics searches like dark matter. Radon also plays a role in generating unwanted backgrounds for the underground experiments. The B.S. in Physics and the Minor in Nuclear Engineering prepares students either for direct employment …
… Breakthrough study reveals insights into how cancer cells evade treatment In the United States, cancer continues to be the second leading cause of death, trailing only heart disease, with millions more afflicted with the disease each year. At South Dakota State University, Rachel Willand-Charnley, assistant professor … "This is a revolutionary piece of work because nobody has uncovered how cancers use sugars to participate in multidrug resistance," Willand-Charnley explained. Sialic acid and cell communication Each cell in the human body has a sugar coat that acts as a shield and the first layer of protection. It's also how cells, both healthy and cancerous, communicate with … from the cell, but the overexpression of acetylated-sialic acids, allowing for the chemotherapeutics to stay inside of the cell. "This highlights the crucial role that sialic acids play in cancer-related multidrug resistance," Willand-Charnley said. Cancers use sugar residues to engage in multidrug resistance. The research conducted by the RAWC Lab reveals …
… South Dakota State University's Haarberg Center for Drug, Disease and Delivery, housed in the College of Pharmacy and Allied Health Professions, has announced its second round of funding for research projects through the Haarberg 3D Center's Pilot Grant Program. The Haarberg 3D Center is funded by the South Dakota Board of Regents, with a goal of advancing interdisciplinary research and research commercialization of biomedical technologies through university, industry and clinical collaborations. Recently, the center also received a $1.1 million gift from Kevin and Lorie … why high-grade serous carcinoma (HGSC) is one of the most common types of "ovarian" cancers and one of the deadliest forms of cancer for women. Understanding the relationship that age plays in ECM remodeling is important but presently has not been well defined. Puente's research project will look to fill in these knowledge gaps while also developing novel …
… Adam Hoppe Research Lab Biochemistry Dr. Adam Hoppe - Associate ProfessorLab's Main Research Areas: Receptor signal transduction and membrane transport controlling the growth and differentiation of macrophages. Recently, we have characterized the endocytic traffic of the Macrophage Colony Stimulating Factor-1 Receptor (CSF-1R), a primary … regulating it. We are working to both elucidate these mechanisms as well as obtain a better understanding of the role of macropinosomes in cell growth. Development of new methods for imaging biochemical events within living cells. Studying biochemistry in living cells requires new ways to observe how and where molecules interact within cells. To this end, we … and Membrane Binding. J. Virol. 83: 7322-7336. Hoppe, A. D., Seveau, S., Swanson, J.A. (2009). Live cell fluorescence microscopy to study microbial pathogenesis. Cell Microbio. 4:540-50. Hoppe, A. D., Shorte, S. L., Swanson, J. A., Heintzmann, R. (2008). 3D-FRET Reconstruction Microscopy for Analysis of Dynamic Molecular Interactions in Live Cells. Biophys. J. …
… an assistant professor in South Dakota State University’s Department of Chemistry, Biochemistry and Physics, has contributed to a book focused on and written by women working in science, technology, engineering and mathematics. “Lessons Learned: Stories from Women Leaders in STEM” addresses the lack of women in STEM through the first-person accounts of … Willand-Charnley explained. Willand-Charnley will be at a book signing from 10 a.m.-noon Saturday, July 15, at The Nook, 314 Main Ave. Suite 3, in downtown Brookings. “In the past 50 years, women in the United States have made great strides in terms of education, representing the majority of college graduates and masters-level programs today. In 2020, for the … fields. While women make up 48% of the workforce, they hold only about 29% of positions in STEM specialties. The book’s contributors—who bucked this trend—share their personal and compelling stories, including obstacles and challenges faced in balancing work, family and personal life,” Shlian added. Shlian, who had been following Willand-Charnley’s career, which …
… Cole-Dai Publications Papers published by Jihong Cole-Dai 2020 Cole-Dai, Jihong , David G. Ferris, Joshua A. Kennedy, Michael Sigl, Joseph R. McConnell, T. J. Fudge, , Kendrick C. Taylor, Joseph M. Souney, Lei Geng, and Olivia J. Maselli (2020), Comprehensive Record of Volcanic Eruptions in the Holocene (11,000 years) from the WAIS Divide, Antarctica ice core, Journal of Geophysical Research-Atmospheres , in poress, doi: … Cole-Dai (2017), Reduced perchlorate concentration in West Antarctica snow during the annual stratospheric ozone hole, Antarctic Science , 29, 292-296, doi:10.1017/S0954102016000705. Mayewski, P. A., A. Carleton, S. Birkel, D. Dixon, A. Kurbatov, E. Korotkikh, J. McConnell, M. Curran, J. Cole-Dai , S. Jiang, C. Plummer, T. Vance, K. Maasch, S. Sneed, M. Handley …
… Science Research Physics Materials and Nanoscience (PMNS) Lab The Physics Materials and Nanoscience (PMNS) Lab at SDSU houses state-of-the-art research facilities to carry out cutting-edge research in novel magnetic materials. Primarily, materials in the form of bulk ingots, single-crystalline films and nanostructured particles for permanent magnets, spintronic devices, magnetic … characterization, preparing them for quality graduate programs or industry jobs. Lab Facilities (Crothers Engineering Hall 350) The facilities in the PMNS lab include: Materials Preparation - two sputtering systems to fabricate multi-layered thin film structures; X-ray structural characterization; Thermal treatment under controlled environment in ultra-high …
… Society in Las Vegas. It is an international gathering with more than 10,000 participants. Their research on Heusler alloys was undertaken at the direction of associate professor Parashu Kharel, who has National Science Foundation funding for the work. The purpose of the work is to find an alloy that will require less battery power for electronic devices such as computers and phones. The students synthesized and tested different alloys in the Kharel’s physics materials and nanoscience lab in Crothers Engineering Hall. Testing didn’t produce … at a nuclear power plant, a hospital or in the space program. Baker is also planning to graduate in May 2024. This summer he plans to continue his research on spintronic and permanent magnet materials under Kharel. His 10-weeks summer research will be partially supported by funds from the National Science Foundation and by NASA EPSCoR. He said was influenced to …
… Research helps SDSU senior refine career path When Sioux Falls native Zachary Lehmann came to South Dakota State University , he set his sights on becoming a medical physicist. “In AP physics class (at Washington High School), I was exposed to the field of medical and health physics, such as radiation therapies for cancer. That … it has been Lehmann’s experiences with research at SDSU and the Mayo Clinic that helped refine his career path. During his second semester at State, associate physics professor Parashu Kharel offered Lehmann an opportunity to do research on semiconductor materials. That experience helped him get a Summer Undergraduate Research Fellowship in molecular … going into medical school or graduate work in biomedical engineering or becoming a research scientist at a hospital or national laboratory working with radiation therapy, medical imagery and nuclear medicine. “Undergraduate research requires commitment and motivation to put in the time and effort to do productive research,” Kharel said. “Zach is a highly …