Saikat Basu

Basu_June2020

Title

Assistant Professor

Office Building

Crothers Engineering Hall

Office

216

Mailing Address

Crothers Engineering Hall 216
Mechanical Engineering-Box 2219
University Station
Brookings, SD 57007

Biography

The Basu Research Group is housed at the Department of Mechanical Engineering at South Dakota State University, and is led by Professor Saikat Basu. He received his PhD in Engineering Mechanics from Virginia Tech in 2014, which was followed by two postdoctoral stints at the Okinawa Institute of Science and Technology (Japan) and at the University of North Carolina Chapel Hill. Dr. Basu started as an assistant professor on tenure-track at SDSU from January 2019.

The group leverages tools from theoretical and computational fluid mechanics to explore interdisciplinary questions. Long-term goal of our research program is to help make computational modeling available as a planning tool for surgeons and clinicians while treating flow-based pathologies. Our work connects applied mathematics and biomathematical modeling, with translational applications in healthcare. Our research revolves around the following tracks -

Track 1: mechanistic transport of topical drugs via physiologic flows,
Track 2: flow physics nuances such as thermal flux and vortices, in the context of clinical transport.

Amongst other topics, we have ongoing projects in the area of vortex wake dynamics, with applications such as flow-induced clean energy innovations and vortex-entrapment of therapeutic particles in clinical flows. For analysis and scientific computations, we use tools from dynamical systems theory. The wake system is reduced to a point vortex-based mathematical model, using a Hamiltonian formalism.

To validate the reliability of our computational and theoretical findings, we frequently collaborate with other experimental groups.

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Dr. Basu's recent collaborative work on interfacial mechanics has been recognized with the Fluid Dynamics Research Prize (2018) of the Japan Society of Fluid Mechanics. His doctoral dissertation on vortex wake dynamics was nominated for the outstanding dissertation award and was also awarded the Paul Torgersen Research Award, both at Virginia Tech. Basu's research on respiratory flow physics has been covered on popular press by ScienceDaily, NewsWise, and by other international media outlets in Europe.

Education

Virginia Tech, Department of Biomedical Engineering and Mechanics: PhD, Engineering Mechanics (2014)
Jadavpur University, India: BE, Civil Engineering (2009)

Academic Responsibilities

Taught courses
- Engineering Mechanics in Biomedical Applications (Fall 2019, SDSU)
- Mechanical Engineering Design (Spring, Fall 2019, SDSU)
- Skeletal Biomechanics (Fall 2018, UNC Chapel Hill)
- Statics (Fall 2017, UNC Chapel Hill)
- Nonlinear Dynamics (Spring 2016, OIST - Japan)
- Statics (Spring 2014, Virginia Tech)
- Fluid Mechanics I, II (Summer 2012, Virginia Tech)

Committee Activities

Member, SDSU Faculty Senate (2019)
Chair, Smithies Nobel Symposium Planning Sub-Committee, UNC Chapel Hill (2017)

Specialty Area

  • Theoretical and Computational Fluid Dynamics

Awards and Honors

- Fluid Dynamics Research Prize (Japan Society of Fluid Mechanics, 2018)
- Nomination for Outstanding Doctoral Dissertation (Virginia Tech, 2015)
- Paul E. Torgersen Research Excellence Award (Virginia Tech, 2013)
- Bechtel Travel Fellowship (Virginia Tech, 2010)
- Pratt Presidential Graduate Fellowship (Virginia Tech, 2009)
- Summer Fellowship (IASc India, 2008)
- Summer Fellowship (JNCASR India, 2007)
- National Merit Scholarship Certificate (India, 2004)

Grants

1. NSF RAPID Grant 2028069 for COVID-19
"Collaborative Research: New Generation of a Bio-inspired Protective Mask Based on Thermal & Vortex Traps"
Period: 05/2020 – 04/2021 | Funds: $199,712
Grant Role: Principal Investigator (with S Jung at Cornell University and L Chamorro at UIUC)

2. Scholarly Dissemination Award from SDSU Office of Academic Affairs
"Use of CFD to track respiratory transport in the throat"
Period: 11/2019 – 05/2020 | Funds: $500
Grant Role: Principal Investigator

3. NIH R01 Subcontract (PI: JS Kimbell, UNC-CH)
"Improving topical drug delivery for treatment of chronic rhinosinusitis using CFD"
Period: 04/2019 - 03/2020 | Funds: $20,021
Grant Role: Subcontract Principal Investigator

4. NIH NCATS Pilot Grant 2KR971701 awarded through UNC-CH
"CFD-based identification of optimal particle sizes for targeted drug delivery at vocal folds"
Period: 02/2018 – 05/2019 | Funds: $2000
Grant Role: Principal Investigator

Professional Memberships

American Physical Society
International Society for Aerosols in Medicine

Work Experience

Assistant Professor, tenure-track: South Dakota State University, USA (01/2019 - Present)
Postdoctoral Fellow: UNC Chapel Hill, USA (2016 - 2018)
Adjunct Faculty: UNC/NC State University, USA (2017 - 2018)
Postdoctoral Scholar: OIST, Japan (2014 - 2016)
Graduate Assistant: Virginia Tech, USA (2009 - 2014)
Summer Intern: DLR - Braunschweig, Germany (2008)

Area(s) of Research

JOURNAL PUBLICATIONS
On vortex dynamics:
1. S Basu and MA Stremler
Exploring the dynamics of 2P wakes with reflective symmetry using point vortices
Journal of Fluid Mechanics, Volume 831, 2017

2. S Basu and MA Stremler
On the motion of two point vortex pairs with wake-inspired glide-reflective symmetry in a periodic strip
Physics of Fluids, Volume 27(10), 2015

3. MA Stremler and S Basu
On point vortex models of exotic bluff body wakes
Fluid Dynamics Research, Volume 46, 2014

4. MA Stremler, A Salmanzadeh, S Basu, and CHK Williamson
A mathematical model of 2P and 2C vortex wakes
Journal of Fluids and Structures, Volume 27(5), 2011

On interfacial mechanics:
5. S Basu, A Yawar, A Concha, and MM Bandi
On angled bounce-off impact of a drop impinging on a flowing soap film
Fluid Dynamics Research, Volume 49, 2017

On applications in healthcare:
6. S Basu, LT Holbrook, K Kudlaty, O Fasanmade, J Wu, A Burke, B Langworthy, M Mamdani, Z Farzal, WD Bennett, J
Fine, BA Senior, AM Zanation, CS Ebert Jr., A Kimple, B Thorp, DO Frank-Ito, GJM Garcia, and JS Kimbell
Numerical evaluation of spray position for improved nasal drug delivery
Accepted for publication at Scientific Reports (open-access journal from Nature), on arXiv: 1909.11960, 2020

7. BM Brandon, WH Stepp, S Basu, JS Kimbell, BA Senior, WW Shockley, and J Madison Clark
Nasal airflow changes with bioabsorbable implant, butterfly and spreader grafts
Accepted for publication at The Laryngoscope, DOI: 10.1002/lary.28691, 2020

8. Z Farzal, S Basu, A Burke, O Fasanmade, E Mamuyac, W Bennett, CS Ebert Jr., A Zanation, BA Senior, and JS Kimbell
Comparative study of simulated nebulized and spray particle deposition in chronic rhinosinusitis patients
International Forum of Allergy & Rhinology, Published online, 2019
DOI: 10.1002/alr.22324

9. LF Tracy, S Basu, P Shah, DO Frank-Ito, S Das, A Zanation, and JS Kimbell
Endoscopic craniofacial resection on simulated nasal airflow and heat transport
International Forum of Allergy & Rhinology, Published online, 2019
DOI: 10.1002/alr.22328

10. JS Kimbell, S Basu, G Garcia, DO Frank-Ito, FB Lazarow, E Su, DE Protsenko, Z Chen, J Rhee, and BJ Wong
Upper airway reconstruction using anatomic optical coherence tomography: effects of airway bend on airflow resistance
Lasers in Surgery and Medicine | Volume 51(2), 2019

11. S Basu, DO Frank-Ito, and JS Kimbell
On computational fluid dynamics models for sinonasal drug transport: relevance of nozzle subtraction and nasal vestibular dilation
International Journal for Numerical Methods in Biomedical Engineering, Volume 34 (4), 2018

12. E Perkins, S Basu, G Garcia, R Buckmire, R Shah, and JS Kimbell
Ideal particle sizes for inhaled steroids targeting vocal granulomas: preliminary study using computational fluid dynamics
Otolaryngology – Head and Neck Surgery, Volume 158(3), 2018

13. BM Brandon, GK Austin, G Fleischman, S Basu, JS Kimbell, WD Shockley, and J Madison Clark
Comparison of airflow between spreader and butterfly grafts using computational fluid dynamics in cadaveric models
JAMA Facial Plastic Surgery, Volume 20(3), 2018

14. JS Kimbell, S Basu, Z Farzal, and BA Senior
Characterizing nasal delivery in 3D models before and after sinus surgery
Respiratory Drug Delivery | Volume 1, 181–188, 2018

15. S Basu. N Witten, and JS Kimbell
Influence of localized mesh refinement on numerical simulations of post-surgical sinonasal airflow
Journal of Aerosol Medicine & Pulmonary Drug Delivery, Volume 30(3), A-14, 2017


Manuscripts in progress (Pre-prints available on request):
16. S Sreenath, JS Kimbell, S Basu, A Coniglio, T Fontenot, B Thorp, CS Ebert Jr., BA Senior, and AM Zanation
Comparative Analysis of the Main Nasal Cavity and the Paranasal Sinuses in Chronic Rhinosinusitis: An Anatomic Study of Maximal Medical Therapy
arXiv preprint: 1811.00649

17. S Basu, R Shah, A Pappa, JWu, A Burke, WD Bennett,WBodnar, and JS Kimbell
Identification of optimal particulate size range for inhaled steroid transmission to laryngeal vocal fold granulomas
through computational fluid dynamics.
In preparation, 2019

Applications of Research

Healthcare Innovations

OPEN POSITIONS
We are looking for motivated undergraduate and graduate students. If the group's research areas align with your general interests, email Prof. Basu (at Saikat.Basu@sdstate.edu) with your CV and a brief outline of your prior research experience, if any.