Saikat Basu

Education

Ph.D., Engineering Mechanics, Virginia Tech (2014)
B.E., Civil Engineering, Jadavpur University, India (2009)

Postdoctoral experience
2016-2018: UNC Chapel Hill
2014-2016: OIST Japan

Academic Interests

Theoretical and Computational Fluid Dynamics

Academic Responsibilities

Taught courses
- Engineering Mechanics in Biomedical Applications (ME 446/546, SDSU)
- Mechanical Design Technologies (ME 212, SDSU)
- Skeletal Biomechanics (Fall 2018, UNC Chapel Hill)
- Statics (Fall 2017, UNC Chapel Hill)
- Nonlinear Dynamics (Spring 2016, OIST Japan)
- Statics (Spring 2014, Virginia Tech)
- Fluid Mechanics I, II (Summer 2012, Virginia Tech)

Committee Activities

Member, NSF Grant Review Panels (2020-Present)
Member, NIH Grant Review Panels (2022-Present)
Member, SDSU College of Engineering Research Council (2023-Present)
Member, SDSU Mechanical Engineering Faculty Search Committee (2022-Present)
Faculty Advisor, Biomedical Engineering Society (BMES) Chapter at SDSU (2022-Present)
Member, SDSU Faculty Senate (2019-2020)
Chair, Smithies Nobel Symposium Planning Sub-Committee, UNC Chapel Hill (2017)

Awards and Honors

- Outstanding Researcher Award (Jerome J. Lohr College of Engineering, South Dakota State University, 2024)
- Faculty Award for International Research (Office of International Affairs, South Dakota State University, 2024)
- Grantswinship Award (Jerome J. Lohr College of Engineering, South Dakota State University, 2023)
- Early Career Investigator of the Year (Jerome J. Lohr College of Engineering, South Dakota State University, 2023)
- Fluid Dynamics Research Prize (Japan Society of Fluid Mechanics, 2018)
- Nomination for Outstanding Doctoral Dissertation (Virginia Tech, 2015)
- Paul Torgersen Research Excellence Award (Virginia Tech, 2013)
- Bechtel Travel Fellowship (Virginia Tech, 2010)
- Pratt Presidential Graduate Fellowship (Virginia Tech, 2009)
- Summer Fellowship (IASc India, 2008)
- Summer Fellowship (JNCASR India, 2007)
- National Merit Scholarship Certificate (India, 2004)

Grants

Extramural awards

10. NSF CAREER Award
CAREER: The Contagion Science: Integration of inhaled transport mechanics principles inside the human upper respiratory tract at multi scales
Period: 01/2024 – 12/2028 | Amount: $540,428
Grant Role: Principal Investigator

9. NIH COBRE RPL Grant
Computational and theoretical fluid mechanics modeling for transport in dense tumors
Period: 03/2023 – 02/2026 | Amount: $450,000
Grant Role: Principal Investigator

8. Industry-Sponsored Project
Sponsored collaboration with Aptar Pharma: Designing targeted carrier solutions for intranasal vaccines
Period: 08/2022 – 05/2024 | Amount: $66,066
Grant Role: Principal Investigator

7. NSF CBET RAPID Grant
Collaborative Research: New Generation of a Bio-inspired Protective Mask Based on Thermal & Vortex Traps
Period: 05/2020 – 04/2022 | Amount: $62,824
Grant Role: Co-Principal Investigator

6. NIH COBRE Pilot Grant
Computational tracking of perfusion in solid tumors
Period: 04/2021 – 07/2022 | Amount: $49,999
Grant Role: Principal Investigator

5. NIH R01 Subcontract from UNC Chapel Hill
Improving topical drug delivery for treatment of chronic rhinosinusitis using CFD
Period: 04/2019 – 03/2020 | Amount: $20,021
Grant Role: Principal Investigator


Intramural awards

4. Haarberg Drug, Disease and Delivery (3D Center) Center Exploratory Grant
Development of a digital platform to assess targeted regional drug delivery for airway sites
Period: 04/2023 – 05/2024 | Amount: $99,710
Grant Role: Principal Investigator

3. Haarberg 3D Center Award for Undergraduate Research Support
'Peak band' vs. 'Monotonic decay': exploring particle deposition and penetration in anatomic cavities
Period: 02/2023 – 06/2023 | Amount: $3,000
Grant Role: Principal Investigator

2. Scholarly Dissemination Award from SDSU Office of Academic Affairs
Use of CFD to track respiratory transport in the throat
Period: 11/2019 – 05/2020 | Amount: $500
Grant Role: Principal Investigator

Before SDSU

1. NIH NCATS Pilot Grant 2KR971701 awarded through UNC-CH
CFD-based identification of optimal particle sizes for targeted drug delivery at laryngeal granulomas
Period: 02/2018 – 05/2019 | Amount: $2,000
Grant Role: Principal Investigator

Professional Memberships

American Physical Society
Biomedical Engineering Society
International Society for Aerosols in Medicine

Work Experience

Assistant Professor, tenure-track: South Dakota State University, USA (01/2019 - Present)
Postdoctoral Fellow: UNC Chapel Hill, USA (2016 - 2018)
Adjunct Faculty: UNC/NC State University, USA (2017 - 2018)
Postdoctoral Scholar: OIST, Japan (2014 - 2016)
Graduate Assistant: Virginia Tech, USA (2009 - 2014)
Summer Intern: DLR - Braunschweig, Germany (2008)

Area(s) of Research

PEER-REVIEWED JOURNAL PUBLICATIONS (h-index = 14, i10-index = 18, as of 03/2024)

26. Z Wu, S Basu, S Kim, M Sorrells, FJ Beron-Vera, S Jung
Coherent spore dispersion via drop-leaf interactions
Science Advances, Volume 10(5): eadj8092, 2024

25. MMH Akash, Y Lao, PA Balivada, P Ato, NK Ka, A Mituniewicz, Z Silfen, J Suman, A Chakravarty, D Joseph-McCarthy, S Basu
On a model-based approach to improve intranasal spray targeting for respiratory viral infections
Frontiers in Drug Delivery, Sec. Respiratory Drug Delivery, Volume 3, 2023

24. MMH Akash, N Chakraborty, J Mohmmad, K Reindl, S Basu
Computational multiphase characterization of perfusion trends inside biomimetic reduced-order dense tumors
Experimental and Computational Multiphase Flow, Volume 5, 2023

23. J Yuk, MMH Akash, A Chakraborty, S Basu, LP Chamorro, S Jung
Morphology of pig nasal structure and modulation of airflow, thermal conditioning, and olfactory functionality
Integrative and Comparative Biology, Volume 63(2), 2023

22. DV Egeren, M Stoddard, A Malakar, D Ghosh, A Acharya, S Mainuddin, B Majumdar, D Luo, R Nolan, D Joseph-McCarthy, LF White, NS Hochberg, S Basu, A Chakravarty
No magic bullet: limiting in-school transmission in the face of variable SARS-CoV-2 viral loads
Frontiers in Public Health, Sec. Infectious Diseases: Epidemiology and Prevention, Volume 10, 2022

21. S Basu, UA Khwaja, SAA Rizvi, MA Sanchez-Gonzalez, G Ferrer
Evaluation of Patient Experience for a Computationally-Guided Intranasal Spray Protocol to Augment Therapeutic Penetration: Implications for Effective Treatments for COVID-19, Rhinitis, and Sinusitis
Medical Research Archives, Volume 10(4), 2022

20. S Basu
Approaching Fermat's Conjecture from the Principle of Mathematical Induction
Logic & Philosophy of Mathematics eJournal, available at SSRN 4023652, 2022

19. J Yuk, A Chakraborty, S Cheng, CI Chung, A Jorgensen, S Basu*, LP Chamorro*, S Jung*
On the design of particle filters inspired by animal noses
Journal of The Royal Society Interface, Volume 19, Article number 20210849 | * all corresponding authors, 2022

18. S Basu, MMH Akash, NS Hochberg, BA Senior, D Joseph-McCarthy, A Chakravarty
From SARS-CoV-2 infection to COVID-19 morbidity: an in silico projection of virion flow rates to the lower airway via nasopharyngeal fluid boluses
Rhinology Online (open-access, peer-reviewed journal from European Rhinologic Society), Volume 5, 2022

17. S Basu
Computational characterization of inhaled droplet transport to the nasopharynx
Scientific Reports (open-access, peer-reviewed journal from Nature), Volume 11, Article number 6652, 2021

16. MA Stremler, S Basu, E Masroor
Streamline patterns in 2P vortex street equilibria
Journal of Fluid Mechanics, Volume 901, 2020

15. S Treat, CS Ebert Jr., Z Farzal, S Basu, AM Zanation, BD Thorp, JS Kimbell, BA Senior, AJ Kimple
Intranasal corticosteroids: patient administration angles and impact of education
Rhinology Online (open-access, peer-reviewed journal from European Rhinologic Society), Volume 3, 2020

14. S Basu, LT Holbrook, K Kudlaty, O Fasanmade, J Wu, A Burke, BW Langworthy, M Mamdani, Z Farzal, WD Bennett, JP Fine, BA Senior, AM Zanation, CS Ebert Jr., A Kimple, B Thorp, DO Frank-Ito, GJM Garcia, JS Kimbell
Numerical evaluation of spray position for improved nasal drug delivery
Scientific Reports (open-access, peer-reviewed journal from Nature), Volume 10, Article number 10568, 2020

13. BM Brandon, WH Stepp, S Basu, JS Kimbell, BA Senior, WW Shockley, J Madison Clark
Nasal airflow changes with bioabsorbable implant, butterfly and spreader grafts
The Laryngoscope, Published online, DOI: 10.1002/lary.28691, 2020

12. Z Farzal, S Basu, A Burke, O Fasanmade, E Mamuyac, W Bennett, CS Ebert Jr., A Zanation, BA Senior, JS Kimbell
Comparative study of simulated nebulized and spray particle deposition in chronic rhinosinusitis patients
International Forum of Allergy & Rhinology, Published online, DOI: 10.1002/alr.22324, 2019

11. LF Tracy, S Basu, P Shah, DO Frank-Ito, S Das, A Zanation, JS Kimbell
Impact of endoscopic craniofacial resection on simulated nasal airflow and heat transport
International Forum of Allergy & Rhinology, Published online, DOI: 10.1002/alr.22328, 2019

Journal publications before SDSU:

10. JS Kimbell, S Basu, GJM Garcia, DO Frank-Ito, FB Lazarow, E Su, DE Protsenko, Z Chen, J Rhee, BJ Wong
Upper airway reconstruction using anatomic optical coherence tomography: effects of airway bend on airflow resistance
Lasers in Surgery and Medicine, Volume 51(2), 2019

9. S Basu, DO Frank-Ito, JS Kimbell
On computational fluid dynamics models for sinonasal drug transport: relevance of nozzle subtraction and nasal vestibular dilation
International Journal for Numerical Methods in Biomedical Engineering, Volume 34 (4), 2018

8. E Perkins, S Basu, GJM Garcia, R Buckmire, R Shah, JS Kimbell
Ideal particle sizes for inhaled steroids targeting vocal granulomas: preliminary study using computational fluid dynamics
Otolaryngology – Head and Neck Surgery, Volume 158(3), 2018

7. BM Brandon, GK Austin, G Fleischman, S Basu, JS Kimbell, WD Shockley, J Madison Clark
Comparison of airflow between spreader and butterfly grafts using computational fluid dynamics in cadaveric models
JAMA Facial Plastic Surgery, Volume 20(3), 2018

6. JS Kimbell, S Basu, Z Farzal, BA Senior
Characterizing nasal delivery in 3D models before and after sinus surgery
Respiratory Drug Delivery, Volume 1, 181–188, 2018

5. S Basu, A Yawar, A Concha, MM Bandi
On angled bounce-off impact of a drop impinging on a flowing soap film
Fluid Dynamics Research, Volume 49, 2017

4. S Basu and MA Stremler
Exploring the dynamics of 2P wakes with reflective symmetry using point vortices
Journal of Fluid Mechanics, Volume 831, 2017

3. S Basu and MA Stremler
On the motion of two point vortex pairs with wake-inspired glide-reflective symmetry in a periodic strip
Physics of Fluids, Volume 27(10), 2015

2. MA Stremler and S Basu
On point vortex models of exotic bluff body wakes
Fluid Dynamics Research, Volume 46, 2014

1. MA Stremler, A Salmanzadeh, S Basu, CHK Williamson
A mathematical model of 2P and 2C vortex wakes
Journal of Fluids and Structures, Volume 27(5), 2011



INDUSTRY COLLABORATIONS (updated 08/2023)
1. Aptar Pharma (Congers, NY)
2. Next Breath (Baltimore, MD)
3. Applied Research Associates (Raleigh, NC)
4. Dr. Ferrer Biopharma (Hallandale Beach, FL)
5. Environmental Medicine, Inc. (Westwood, NJ)
6. Fractal Therapeutics (Lexington, MA)
7. Innoveyda (Foothill Ranch, CA)
8. MedScience Research Group, Inc. (West Palm Beach, FL)

Applications of Research

Bridging the ENG-MED disconnect through discoveries and extensions from classical fluid mechanics and biomathematical modeling, with core contributions in areas of airborne transmission of diseases through respiratory routes and cancer flow physics