Skip to main content
Menu
Close Search

Jane Hennings

Photo of Jane Hennings
Title Department Head/Director/Professor
Office Building Animal Disease Research & Diagnostic Laboratory
Room Number 105
Mailing Address South Dakota State University
Veterinary & Biomedical Sciences
SAR 105, Box 2175
Brookings, SD 57007
Download CV

Applications of Research

Book Chapters
1. Christopher-Hennings J., G. Erickson, R. Hesse, Simone Oliveira, E. Nelson. 2012. Diagnostic tests, test performance and considerations for interpretation. In: Diseases of Swine (10th edition). Wiley-Blackwell, Inc., p 77-93.
2. Fang, Y., K.S. Faaberg, J. Christopher-Hennings, R.R. Rowland, A.K. Pattnaik, F.A. Osorio and E.A. Nelson. 2006. Construction of a European-like type 1 PRRSV full-length cDNA infectious clone identified in the United States, in: The Nidoviruses: The Control of SARS and Other Nidovirus Diseases. Pearlman and Holmes (editors) Springer Publishers, Adv. Exp. Med. Bio. 581:605-608.
3. Yoon, K.-J., J. Christopher-Hennings and E.A. Nelson. 2003. Diagnosis of PRRS virus. In: 2003 PRRS Compendium – Chapter 7. J. Zimmerman, K.-J. Yoon and E. Neumann, eds. National Pork Board.
4. Yoon, K.-J., J. Christopher-Hennings and E.A. Nelson. 2003. Diagnosis of PRRS virus. In: 2003 PRRS Compendium – Producer Edition. J. Zimmerman, K.-J. Yoon and E. Neumann, eds. National Pork Board.
5. Christopher-Hennings J. and E. A. Nelson. PCR analysis for the identification of porcine reproductive and respiratory syndrome virus in boar semen. In: PCR in Bioanalysis. Walker, J. M. ed. Humana Press (Methods in Molecular biology Series). p. 81-88, 1998.
6. Nelson, E. A., J. Christopher-Hennings, D. A. Benfield. 1995. Structural proteins of porcine reproductive and respiratory syndrome virus. In: Talbot, P. J. and Levy, G. A., eds. Corona and Related Viruses. New York: Plenum Publishing Corporation. p. 232-234.

Area(s) of Research

Additional Presentations and Abstracts

1. Trevisan G., L. Linhares, B Crim; P Dubey, K Schwartz, E Burrough, R Main, P Sundberg, M Thurn, P Lages, K VanderWaal, A Perez, J Torrison, J Henningson, E Herrman, G Hanzlicek, R Raghavan, D Marthaler, J Greseth, T Clement, J Christopher-Hennings, D Linhares.
Swine Disease Reporting System: real-time, aggregated results from major US veterinary diagnostic laboratories. Jim McKean Swine Disease Conference.
2. Dee, S., F. Bauermann, M. Niederwerder, A. Singrey, M. de Lima, G. Patterson, S. Dritz, M. Tokach, J. Woodworth, C. Jones, J. De Jong, G. Spronk, J. Christopher-Hennings, J. Ji, J. Zimmerman, R. Rowland, E. Nelson, P. Sundberg, D. Diel. Evaluation of the survival of viral pathogens in contaminated feed ingredients using transboundary shipment models. Abstract #78. Conference of Research Workers in Animal Diseases. Dec. 3-5, 2017. Chicago, IL.
3. Dee, S., F. Bauermann, M. Niederwerder, A. Singrey, T. Clement, M. de Lima, C. Long, G. Patterson, M. Sheahan, A. Stoian, V. Petrovan, C. Jones, J. De Jong, J. Ji, G. Spronk, J. Christopher-Hennings, J. Zimmerman, R. Rowland, E. Nelson, P. Sundberg, D. Diel. Survival of viral pathogens in animal feed ingredients under transboundary shipping models. Abstract # S3. North American PRRS Symposium. Dec. 1-3, 2017. Chicago, IL.
4. Clement, T., R. Rauh, W. Nelson, J. Kelly, E. Nelson, J. Christopher-Hennings. A cost effective method for surveillance of PRRSV and IAV-S in oral fluids using a newly developed multiplex rtRT-PCR. NA PRRS Symposium, Dec. 3-4, 2016, Chicago, IL, P 2.
5. Lawson, S. A. Singrey, L. Joshi, J. Leat, J. Nelson, D.G. Diel, J. Christopher-Hennings, E.A. Nelson. Development of antibody reagents and assays for Senecavirus A serodiagnosis. NA PRRS Symposium, Dec. 3-4, 2016, Chicago, IL, P 10.
6. Dee, S., G. Spronk, E. Nelson, D. Diel, T. Clement, A. Singrey, F. Bauermann, J. Hennings, C. Jones, R. Cochrane, G. Patterson. Modeling the transboundary survival of foreign animal disease pathogens in contaminated feed ingredients. NA PRRS Symposium, Dec. 3-4, 2016, Chicago, IL, P 93.
7. Lawson, S., L. Joshi, M.F. Maggioli, M.H.V. Fernandes, F. Okda, J. Christopher-Hennings, E.A. Nelson, D.G. Diel. Immune responses to Senecavirus A in pigs. Conf. of Research Workers in Animal Disease, Dec. 4-6, 2016, Chicago, IL, 190.
8. Fernandes, M.H.V., F. Okda, L.R. Joshi, K.S. Hain, E.A. Nelson, J. Christopher-Hennings, F.A. Osorio, H. Vu, D.G. Diel. Evaluation of immunodominant B- and T-cell epitopes as inducers of protective immunity against porcine reproductive and respiratory syndrome virus. Conf. of Research Workers in Animal Disease, Dec. 4-6, 2016, Chicago, IL, P53.
9. Lawson, S. A. Singrey, L. Joshi, J. Leat, J. Nelson, D.G. Diel, J. Christopher-Hennings, E.A. Nelson. Development of antibody reagents and assays for Senecavirus A serodiagnosis. Conf. of Research Workers in Animal Disease, Dec. 4-6, 2016, Chicago, IL, P80.
10. Lawson, S.R., A. Singrey, D.G. Diel, J. Leat, L.R. Joshi, J. Nelson, J. Christopher-Hennings, E.A. Nelson. Development of reagents and assays for Senecavirus A serodiagnosis. Proc. 59th Ann. Meet. American Association of Veterinary Laboratory Diagnosticians, Greensboro, NC, Oct. 2016. p.219.
11. Joshi, L.R., S.R. Lawson, M.H.V. Fernandes, J. Christopher-Hennings, E.A. Nelson, D.G. Diel. Serological responses to Senecavirus A infection in pigs. Proc. 59th Ann. Meet. American Association of Veterinary Laboratory Diagnosticians, Greensboro, NC, Oct. 2016. p.125.
12. Dee, S., C. Neill, A. Singrey, T. Clement, R. Cochrane, C. Jones, G. Patterson, G. Spronk, J. Christopher-Hennings, E. Nelson. Modeling the transboundary risk of feed ingredients contaminated with porcine epidemic diarrhea virus. American Assoc. of Swine Veterinarians. Feb. 27-Mar 1, 2016. New Orleans, LA. P. 421.
13. Thomas, M., A. Thachil, S. Ghimire, A. Glaser, A. Pillatzki, E. Nelson, J. Christopher-Hennings, R. Daly, J. Scaria. Genotypic and phenotypic characterization of Salmonella enterica serovar Dublin in cattle. Proc. 59th Ann. Meet. American Association of Veterinary Laboratory Diagnosticians, Greensboro, NC, Oct. 2016.
14. Dee, S., C. Neill, A. Singrey, T. Clement, A. Singrey, J. Christopher-Hennings, E. Nelson. An evaluation of porcine epidemic diarrhea virus survival in individual feed ingredients in the presence or absence of a liquid antimicrobial. American Assoc. of Swine Veterinarians. Feb. 27-Mar 1, 2016. New Orleans, LA. P.54-56.
15. Dee, S. C. Neill, T. Clement, A. Singrey, J. Christopher-Hennings, E. Nelson. An evaluation of porcine epidemic diarrhea virus survival in individual feed ingredients in the presence or absence of a liquid antimicrobial. NA PRRS Symposium, Dec. 5-6, 2015, Chicago, IL, P 85.
16. Lawson, S., F. Okda, X. Liu, A. Singrey, T. Clement, J. Christopher-Hennings, E.A. Nelson. Development of indirect and blocking ELISAs for detection of antibodies against porcine epidemic diarrhea virus (PEDV). 23rd Congress of the International Pig Veterinary Society, June 8-11, 2014, Cancun, Mexico. Abstract #1937.
17. Singrey, A., S. Lawson, F. Okda, X. Liu, T. Clement, J. Nelson, J. Christopher-Hennings, E.A. Nelson. Development and diagnostic application of monoclonal antibodies to porcine epidemic diarrhea virus (PEDV). 23rd Congress of the International Pig Veterinary Society, June 8-11, 2014, Cancun, Mexico. Abstract #1938.
18. Nelson, J., F. Okda, R. Parmar, A. Singrey, S. Lawson, X. Liu, J. Christopher-Hennings, E.A. Nelson. Environmental stability of a cell culture adapted U.S. isolate of porcine epidemic diarrhea virus (PEDV). 23rd Congress of the International Pig Veterinary Society, June 8-11, 2014, Cancun, Mexico. Abstract #1940.
19. Caya, I., M. Bertrand, A. Broes, S. Lawson, E.A. Nelson, J. Christopher-Hennings. Development of an indirect enzyme-linked immunosorbent assay (ELISA) for detection of antibodies against porcine epidemic diarrhea virus (PEDV). AAVLD, Kansas City, MO, Oct. 2014. p.191.
20. Lawson, S. F. Okda, X. Liu, A. Singrey, T. Clement, J. Christopher-Hennings, E.A. Nelson. Development of a fluorescent microsphere immunoassay (FMIA) and a blocking ELISA for detection of antibodies against porcine epidemic diarrhea virus (PEDV). AAVLD, Kansas City, MO, Oct. 2014. p.193.
21. Singrey, A., S. Lawson, F. Okda, X. Liu, T. Clement, J. Nelson, J. Christopher-Hennings, E.A. Nelson. Development and diagnostic application of monoclonal antibodies against porcine epidemic diarrhea virus (PEDV). AAVLD, Kansas City, MO, Oct. 2014. p.192.
22. Dee, S., T. Clement, A. Schelkopf, J. Nerem, D. Knudsen, J. Christopher-Hennings, E. Nelson. An evaluation of contaminated complete feed as a vehicle for porcine epidemic diarrhea virus infection of naïve pigs following consumption via natural feeding behavior: Proof of concept. North American PRRS Symposium, Chicago, IL, Dec. 2014. p.116.
23. Dee, S., C. Neill, T. Clement, J. Christopher-Hennings, E. Nelson. An evaluation of a liquid antimicrobial (Sal CURB®) for reducing the risk of porcine epidemic diarrhea virus infection of naïve pigs during consumption of contaminated feed. North American PRRS Symposium, Chicago, IL, Dec. 2014. p.117.
24. Dee, S., T. Clement, A. Singrey, J. Christopher-Hennings, E. Nelson. An evaluation of a liquid antimicrobial (Sal CURB®) for reducing the risk of viral proxies for foreign animal diseases in contaminated feed. North American PRRS Symposium, Chicago, IL, Dec. 2014. p.118.
25. Dee, S., T. Clement, J. Christopher-Hennings, E. Nelson. Assessing the viability of porcine epidemic diarrhea virus in dry feed at 4 degrees C. North American PRRS Symposium, Chicago, IL, Dec. 2014. p.119.
26. Singrey, A., S. Lawson, F. Okda, K. Hain, T. Clement, J. Christopher-Hennings, E.A. Nelson. Development of monoclonal antibodies and other reagents for detection of porcine deltacoronavirus (PDCoV). North American PRRS Symposium, Chicago, IL, Dec. 2014. p.53.
27. Okda, F., S. Lawson, A. Singrey, X. Liu, J. Nelson, J. Christopher-Hennings, E.A. Nelson. Development of serological assays for detection of antibodies against porcine deltacoronavirus (PDCoV). North American PRRS Symposium, Chicago, IL, Dec. 2014. p.51.
28. Lawson, S., F. Okda, X. Liu, A. Singrey, T. Clement, J. Christopher-Hennings, E.A. Nelson. Development of an indirect ELISA, a fluorescent microsphere immunoassay (FMIA) and a blocking ELISA for detection of antibodies against porcine epidemic diarrhea virus (PEDV). North American PRRS Symposium, Chicago, IL, Dec. 2014. p.48.
29. Singrey, A., S. Lawson, F. Okda, K. Hain, T. Clement, J. Christopher-Hennings, E.A. Nelson. Development of monoclonal antibodies and other reagents for detection of porcine deltacoronavirus (PDCoV). 95th Conference of Research Workers in Animal Diseases, Chicago, IL, Dec. 2014. 083P.
30. Stricker M, D Polson, J Christopher-Hennings; T Clement. Variation in PRRS virus ORF5 sequencing within and among 3 state diagnostic laboratories, American Association of Swine Veterinarians, San Diego, CA, March 2013.
31. Olsen C, Karriker L, Wang C, Abate S, Binjawadagi B, Christopher-Hennings J, Doolittle K, Harmon K, Kittawornrat A, Kurtz A, Kurtz E, Lizano S, Coetzee J, Main R, Meiszberg A, Nelson E, Otterson T, Panyasing Y, Rademacher C, Rauh R, Renukaradhya G, Shah R, Zimmerman J. Effect of sample collection material on the detection of PRRSV in oral fluid. 93rd Annual Meeting of the Conference of Research Workers in Animal Diseases, December 2-4, 2012. Chicago, IL. Abstract 160.
32. Olsen C, Karriker L, Wang C, Abate S, Binjawadagi B, Christopher-Hennings J, Doolittle K, Harmon K, Kittawornrat A, Kurtz A, Kurtz E, Lizano S, Coetzee J, Main R, Meiszberg A, Nelson E, Otterson T, Panyasing Y, Rademacher C, Rauh R, Renukaradhya G, Shah R, Zimmerman J. Effect of sample collection material on the detection of PRRSV in oral fluid. 2012 International PRRS Symposium, November 29-30, 2012. Poster 29.
33. Olsen C, Wang C, Christopher-Hennings J, Doolittle K, Kittawornrat K, Kurtz A, Kurtz E, Lizano A, Main R, Otterson T, Panyasing Y, Rademacher C, Rauh R, Shah R, Zimmerman J. Probability of detecting PRRSV infection using pen-based swine oral fluid specimens as a function of within-pen prevalence. 2012 International PRRS Symposium, November 29-30, 2012. Poster 28.
34. Olsen C, Karriker L, Wang C, Abate S, Binjawadagi B, Christopher-Hennings J, Doolittle K, Harmon K, Kittawornrat A, Kurtz A, Kurtz E, Lizano S, Coetzee J, Main R, Meiszberg A, Nelson E, Otterson T, Panyasing Y, Rademacher C, Rauh R, Renukaradhya G, Shah R, Zimmerman J. November 9, 2012. Swine Oral Fluid Diagnostics Update. Proceedings of the 20th Annual Swine Disease Conference for Swine Practitioners. November 2012. Ames, IA p. 89
35. Olsen, C, C Wang, J Christopher-Hennings, K Doolittle, A Kittawonrnrat, A Kurtz, E Kurtz, S Lizano, R Main, T Otterson, Y Panyasing, C Rademacher, R Rauh, R Shah, J Zimmerman. Probability of detecting PRRSV infection using pen-based swine oral fluid specimens as a function of within-pen prevalence. Conference for Research Workers in Animal Diseases, NC-229, Chicago, IL, December 2012, Abstract 161.
36. C Olsen, L Karriker, C Wang, B Binjawadagi J Christopher-Hennings, K Doolittle, K Harmon, S Jones, A Kittawornrat, A Kurtz, E Kurtz, S Lizano, J Coetzee, R Main, A Meiszberg, E Nelson, T Otterson, Y Panyasing, C Rademacher, R Rauh, G Renukaradhya, R Shah, J Zimmerman. Swine Oral Fluid Diagnostics Update. Swine Disease Conference for Swine Practitioners. Ames, IA. November 2012.
37. Olsen C, Wang C, Christopher-Hennings J, Doolittle K, Harmon K, Abate S, Kittawornrat A, Lizano S, Main R, Nelson E, Otterson T, Panyasing Y, Rademacher C, Rauh R, Shah R, Zimmerman J. September 18, 2012. Oral fluids: Detection of PRRSV as a function of within pen prevalence. Allen D. Leman Swine Conference. St. Paul, Minnesota. September 2012.
38. Wang X, H Zhang, X Guo, E Nelson, J. Christopher-Hennings. Porcine reproductive and respiratory syndrome virus activates the transcription of interferon alpha/beta in monocyte-derived dendritic cells. American Association of Virology, Madison, WI, July 2012.
39. Langenhorst R, S Lawson, A Kittawornrat, J Zimmerman, Z Sun, Y Li, J. Christopher-Hennings, E Nelson, Y. Fang. Development of a fluorescent microsphere immunoassay for detection of antibodies against porcine reproductive and respiratory syndrome virus using oral fluid samples as an alternative to serum-based assays. American Association of Virology, Madison WI, July 2012.
40. Christopher-Hennings J. Development of a swine-specific multiplexed cytokine assay for use in the boar—a potential biomedical model of viral infection in semen. Graduate Women in Science (GWIS) 91st National Conference, Madison, WI, June 2012.
41. Hanmo Zhang, Xueshui Guo, Eric Nelson, Jane Christopher-Hennings, Xiuqing Wang Porcine Reproductive and Respiratory Syndrome Virus Activates the Transcription of Interferon alpha/beta (IFN-α/β) in Monocyte-derived Dendritic Cells. Proc ASV 2012.
42. Anderson, T., Goldberg, T., Laegried, W., Christopher-Hennings, J., Nelson, E., Osorio, F. Weapons of mess-reduction: applying network statistics to define core PRRSV sequences for rational polyvalent vaccine development. Proc. IPRRSS 2010.
43. Anderson T.K., Laegreid W., Cerutti F., Osorio F.A., Nelson E.A., Christopher-Hennings J., Goldberg T. Weapons of mess-reduction: Applying Network Statistics to Define Core PRRSV Sequences for Rational Polyvalent Vaccine Development. Proc ASV 2011. Minneapolis, MN.
44. Irwin CK, Zimmerman J, Christopher-Hennings J, Harmon K, Kitikoon P, McGill J, Otterson T, Rauh R, Shah R, Skarbek. 2011. Detection of influenza A virus in oral fluid ring test samples by RT-PCR. Proc Emerg Dis 2011, p. 284.
45. Langenhorst R, Lawson S, Kittawornrat A., Zimmerman J, Sun Z, Li Y, Christopher-Hennings J, Nelson E, Fang Y. 2011.Simultaneous detection of antibodies against PRRSV nsp7 and nucleocapsid protein in swine oral fluid and sera using a fluorescence microsphere immunoassay. Proc. Nidovirus. Grand Traverse, MI.
46. Lawson S, Li Y, Patton J, Langenhorst R. Sun Z, Jiang Z, Christopher-Hennings J, Nelson E, Knudsen D, Fang Y, Chang K-O. 2011. Interleukin 1B expression by a recombinant PRRSV enhanced viral specific host immunity. Proc. Nidovirus. Grand Traverse, MI.
47. Irwin CK, Zimmerman J, Christopher-Hennings J, Harmon K, Kitikoon P, McGill J, Otterson T, Rauh R, Shah R, Skarbek K. June 2011. Detection of influenza A virus in oral fluid ring test samples by RT-PCR. Proc 6th International Symposium on Emerging and Re-emerging Pig Diseases. Barcelona, Spain, p. 284.
48. Irwin C, Zimmerman J, Wang C, Hesse R, Harmon K, Christopher-Hennings J, Otterson T, McGill J, Vincent A, Shah R, Rauh R. October 2011. Real-Time rt-PCR detection of influenza A Virus in oral fluid using a check test. Proc. 54th Annual Conference American Association of Veterinary Laboratory Diagnosticians. Buffalo, NY, p. 153.
49. Christopher-Hennings J. Diagnostic Laboratory Update, Swine Influenza Testing and Molecular Diagnostics Update. January 2011.
50. Irwin CK, Prickett JR, Zimmerman J, Bosworth B, Harris DL, Christopher-Hennings J. March 2010. RT-PCR detection of H3N2 influenza virus in oral fluid samples from experimentally infected pigs. Proceedings of the American Association of Swine Veterinarians. Omaha, Nebraska, pp. 365-366.
51. Christopher-Hennings J. 2010. “A historical perspective on applying science for the diagnosis and control of PRRSV”
a. Institute of Animal Science & Veterinary Medicine, China Academy of Agricultural Sciences, Shanghai, China
b. Shanghai Veterinary Research Institute, Shanghai Academy of Agricultural Sciences, Shanghai, China
c. Huazhong Agriculture University, Wuhan, China
d. Northwest Forestry and Agriculture University, Xian, China
e. China Agriculture University, Beijing, China
f. China Institute of Veterinary Drug Control/Center for Veterinary Drug Evaluation, Beijing, China
g. Institute of Microbiology, Chinese Academy of Science, Beijing, China
52. Lawson S, J Lunney, Y Fang, E. Nelson, J Christopher-Hennings. 2009. Development of a rapid, swine-specific test to simultaneously detect multiple immune proteins (cytokines) affected by porcine reproductive and respiratory syndrome virus (PRRSV) infection. Conference for Research Workers in Animal Diseases & International PRRSV Symposium, Chicago, IL.
53. Lunney J, R Rowland, Z Chen, X Zhou, S Lawson, Z Sun, E Brown, J Christopher-Hennings, D Knudsen, E. Nelson Y. Fang. 2009. Genetic approaches to reveal immune response pathways and viral antigen targets for novel vaccine design. Veterinary Vaccines and Diagnostics Conference (IVVDC), July 19-23, 2009, Madison, WI
54. Irwin C, J Prickett, JJ Zimmerman, B Bosworth, J Christopher-Hennings. 2009. RT-PCR detection of H3N2 influenza virus in oral fluid samples from experimentally infected pigs. American Association of Veterinary Laboratory Diagnosticians, San Diego, CA.
55. Reister L, T Clement, E Nelson, J Christopher-Hennings. 2008. Potential mechanical and antiviral methods to insure PRRSV free semen. Conference for Research Workers in Animal Diseases & International PRRSV Symposium, Chicago, IL.
56. Chen Z, X Zhou, S Lawson, E Brown, R Breen J. Christopher-Hennings, E Nelson, Y Fang. 2008. Expression of foreign proteins in replicase gene regions of porcine reproductive and respiratory syndrome virus. Conference for Research Workers in Animal Diseases & International PRRSV Symposium, Chicago, IL.
57. Molina RM, W Chittick, EA Nelson, J Christopher-Hennings, RRR Rowland, JJ Zimmerman. 2007. Diagnostic performance of assays for the detection of anti-PRRSV antibodies in muscle transudate (“meat juice”) samples. Conference for Research Workers in Animal Diseases & International PRRSV Symposium, Chicago, IL.
58. Molina RM, W Chittick, EA Nelson, J Christopher-Hennings, R Hesse, RRR Rowland, JJZimmerman. 2007. Failure to transmit PRRSV via consumption of PCR-positive meat. Conference for Research Workers in Animal Diseases & International PRRSV Symposium, Chicago, IL.
59. Lunney JK, D Kuhar, E Prucnal, R Molina, J Christopher-Hennings, E Nelson, J Zimmerman, RRR Rowland. Swine immunity and resistance to persistent PRRSV. Conference for Research Workers in Animal Diseases & International PRRSV Symposium, Chicago, IL.
60. Fang Y, XF Gao, JJ Bao, E Brown, RR Rowland, J Christopher-Hennings, E Nelson. 2007. PRRSV non-structural protein : Potential functions in viral replication and pathogenesis. Conference for Research Workers in Animal Diseases & International PRRSV Symposium, Chicago, IL.
61. Christopher-Hennings J., T. Clement, E. Nelson, J. Lunney. 2007. Viral infection of semen: The boar as a model. HIV Persistence during Therapy, Global Antiviral Journal. 3rd International Workshop. St. Maarten, West Indies.
62. Zimmerman J, Molina RM, Rowland RRR, Christopher-Hennings J, Nelson E, Lunney J, Yoon K-J, Murtaugh MP, Chittick W. 2007. “Big Pig” evaluations - Lessons learned. Swine Disease Conference for Swine Practitioners, Iowa State University. Ames, Iowa.
63. Molina RM, Rowland RRR, Christopher-Hennings J, Nelson E, Lunney J, Yoon K-J, Murtaugh MP, Chittick W, Zimmerman J. 2007. “Big Pig” evaluations - Lessons learned. Proceedings 15th Annual Swine Disease Conference for Swine Practitioners, Iowa State University. Ames, Iowa, pp. 122-124.
64. Bao J., X. Gao, E. Brown, J. Christopher-Hennings, H. Liu, R. Daly, D. Knudsen, E. Nelson, B. Berkenpas, R. Breen, Y. Fang. 2007. Genetic marker development in the Nsp2 region of a US type 1 PRRSV. Conference for Research Workers in Animal Diseases, Chicago, IL.
65. Clement T., A. Rovira, C. Munoz-Zanzi, J. Lunney, E. Nelson, J. Christopher-Hennings. 2007. Presence of IL-12 in seminal plasma from PRRSV infected and non-infected boars. International PRRSV Symposium, Conference for Research Workers in Animal Diseases, Chicago, IL.
66. Rovira A., C. Munoz-Zanzi, J. Christopher-Hennings. 2006 & 2007. Evaluation of sensitivity of PCR to detect PRRSV. International PRRSV Symposium, Chicago, IL 2006 & PRRSV CAP Program, American Association of Swine Veterinarians, Orlando, FL 2007.
67. Zuckermann, F., E. Alvarez Garcia, I. Luque, J. Christopher-Hennings, A. Doster, M. Brito, F. Osorio. 2006. Assessment of the efficacy of commercial porcine reproductive and respiratory syndrome virus (PRRSV) vaccines based on measurement of serologic response, frequency of gamma-IFN producing cells and virological parameters of protection upon challenge. International PRRSV Symposium, Conference for Research Workers in Animal Diseases, Chicago, IL.
68. J. Schwartz, N. Benson, B. Neiger, H. X. Liu, R. R. Rowland, D. A. Benfield, J. Christopher-Hennings, E. A. Nelson, Y. Fang. 2006. Evaluation of the cysteine protease domain of PRRSV Nsp2 as a potential new antigen for ELISA development. International PRRSV Symposium, Conference for Research Workers in Animal Diseases, Chicago, IL.
69. Lunney J., R.R.R. Rowland, R. Molina, J. Hermann, D. Kuhar, J. Christopher-Hennings, E. Nelson, V. Leathers, J. Zimmerman. 2006. Do immune genes indicate which pigs will have persistent PRRSV infections? International PRRSV Symposium, Conference for Research Workers in Animal Diseases, Chicago, IL.
70. Fang Y., K. Faaberg, J. Christopher-Hennings, R.R. Rowland, A. K. Pattnaik, F.A. Osorio, E. A. Nelson. 2005. Construction of a European-like type 1 PRRSV full-length cDNA infectious clone identified in the United States. Xth International Nidovirus Symposium, Colorado Springs, CO.
71. Christopher-Hennings J., J. Callahan, A. Wasilk, T. Gay, Y. Fang, M. Dammen, M. Torremorell, D. Polson, M. Mellencamp, E. Nelson, Wm. Nelson. 2004. Quantification of porcine reproductive and respiratory syndrome virus in boar serum and semen. American Association of Veterinary Laboratory Diagnosticians, Greensboro, NC.
72. Fang Y., B. Neiger, T. Hawkins, J. Christopher-Hennings, R.R.R. Rowland, E.A. Nelson. 2004. Preparation of monoclonal antibodies against the NSP2 protein of European-like PRRSV: Establishment of a panel of monoclonal antibodies to differentiate European-like PRRSV from North American and European type PRRSV. 85th Conference of Research Workers in Animal Diseases. P.78. Chicago, IL.
73. Mangold B, S Weeks, T Calvin, W Nelson, J. Christopher-Hennings. 2004. Direct evaluation of bovine fecal samples for Mycobacterium avium subsp. paratuberculosis by a real-time PCR commercial assay. American Association of Veterinary Laboratory Diagnosticians p. 84.
74. Zimmerman J., D. Benfield, J. Christopher-Hennings, S. Dee, G. Stevenson. 2004. Porcine Reproductive and Respiratory Syndrome. Pork Industry Handbook.
75. Christopher-Hennings J. J. Callahan, A. Wasilk, T. Gay, Y. Fang, M. Dammen, M. Torremorell, D. Polson, M. Mellencamp, E. Nelson, W. Nelson. 2004. Development, validation, and commercialization of a real-time PCR for the detection of Lelystad, European-like and US PRRSV. American Association of Swine Veterinarians, Des Moines, IA.
76. Fang, Y., W.P. Zhang, R.R.R. Rowland, J. Christopher-Hennings and E.A. Nelson. 2003. Phylogeny of European-like PRRSV isolates in North America. 84th Conf. of Research Workers in Animal Disease. Chicago, IL.
77. Christopher-Hennings J. 2003. PCR testing of boar semen. Pipestone Reader. 1 (2), 3rd quarter.
78. Fang, Y., D. Kim, R.R.R. Rowland, S. Ropp, P. Steen, J. Christopher-Hennings and E.A. Nelson. 2003. Heterogeneity in the NSP2 gene of European-like PRRSV isolated in the United States. 84th Conf. of Research Workers in Animal Disease. Chicago, IL.
79. Christopher-Hennings, J., J. Callahan, T. Gay, A. Wasilk, Y. Fang, M. Dammen, M. Torremorell, D. Polson, M. Mellencamp, E.A. Nelson and W.M. Nelson. 2003. Validation of a real-time, quantitative PCR assay to detect U.S. and Lelystad/European-like PRRSV in boar semen and serum. 84th Conf. of Research Workers in Animal Disease. Chicago, IL.
80. Paige B., Y. Fang, S. Ropp, N. Ferrin, A. Wasilk, P. Steen, J. Christopher-Hennings, E. Nelson. 2003. Identification of European-like PRRS virus in the United States. Proceedings of the South Dakota Academy of Sciences 82:267.
81. K-J Yoon, J. Christopher-Hennings, E. A. Nelson. Diagnosis of PRRSV (chapter 7). In: 2003 PRRSV Compendium. Zimmerman J., Neumann E., eds. National Pork Board, 2003. p. 57-67, 2003.
82. Callahan J. D., J. Christopher-Hennings, T. A. Gay, M. E. Reos, Y. Fang, M. Dammen, A. Wasilk, J. Galeota, F. A. Osorio, M. Torremorell, W. M. Nelson, E. A. Nelson. 2003. Development, validation and commercialization of a real-time RT-PCR for the detection of Lelystad, European-like and U.S. Porcine Reproductive and Respiratory Syndrome Viruses. American Association of Veterinary Laboratory Diagnosticians. San Diego, CA.
83. Christopher-Hennings J., M. Dammen, S. Weeks, G. Steinlicht, J. Payeur, E. Nelson. 2003. Nested PCR combined with a commercial extraction achieves a sensitivity equal to culture for the detection of Mycobacterium avium subsp. paratuberculosis directly from bovine feces. American Association of Veterinary Laboratory Diagnosticians. San Diego, CA.
84. Ropp, S. L., Y. Fang, M. Bien, B. Arndt, S. Preszler, P. Steen, J. Christopher-Hennings, D. A. Benfield, E. A. Nelson. 2002. Antigenic and genetic characterization of emerging European-like PRRSV isolates in the United States. Conference for Research Workers in Animal Diseases. St. Louis, MO.
85. Carlson, D., Y. Fang, E. Nelson, J. Christopher-Hennings. 2002. Discriminating between PRRSV isolates and vaccine with quantitative, real-time RT-PCR. American Association of Veterinary Laboratory Diagnosticians. St. Louis, MO.
86. Skaare J., Y. Fang, M. Dammen, S. Weeks, W. Epperson, S. Singh, G. Steinlicht, J. Larsen, J. Payeur, E. Nelson, J. Christopher-Hennings. 2002. Comparison of two DNA extractions and nested PCR, real-time PCR, a new commercial PCR assay and bacterial culture for detection of Mycobacterium avium sbsp. paratuberculosis in bovine feces. American Association of Veterinary Laboratory Diagnosticians, St. Louis, MO.
87. Carroll, J., Y. Fang, N. Ferrin, J. Christopher-Hennings, M.P. Murtaugh and E. A. Nelson. 2001. Preliminary validation of a blocking ELISA for detection of antibodies against PRRSV. 82nd Conference of Research Workers in Animal Disease.
88. Beckler D. C., D. R. Baker, J. Christopher-Hennings, D. H. Zeman, D. H. Francis. 2001. Age- and site-specific colonization of porcine small intestinal epithelium by K88-fimbriated enterotoxigenic Escherichia coli in the ligated loop model. Conference for Research Workers in Animal Diseases, Chicago, IL.
89. Wu W.-H., Y. Fang, J. Larsen, E. Nelson, J. Christopher-Hennings. 2000. Molecular Beacons: a new approach for detecting Mycobacterium paratuberculosis in bovine fecal samples. Conference for Research Workers in Animal Diseases. Chicago, IL.
90. Christopher-Hennings, J., L. Holler and E.A. Nelson. 2000. Detection and duration of PRRSV in semen, serum, PMBC and tissues from Yorkshire, Hampshire and Landrace boars. Proceedings of the Allen D. Leman Swine Conference.
91. Wu, W.-H., J. Christopher-Hennings and E.A. Nelson. 2000. Expression of a small structural protein expressed from the ORF 2 transcript of PRRSV. VIIIth International Symposium on Nidoviruses. Lake Harmony, PA.
92. Wu W.-H., J. Christopher-Hennings, E. A. Nelson. 2000. Identification of a Small Structural Protein Expressed from the ORF 2 Transcript of PRRSV. American Society for Virology. Colorado State University, Ft. Collins, CO.
93. Yousif A., S. Aus, L. Braun, J. Christopher-Hennings, C. Chase. 2000. Pestivirus NS3 Type-specific Molecular Beacons. American Society for Virology. Colorado State University, Ft. Collins, CO.
94. Fraser T. J., J. Christopher-Hennings, K. Rossow, E. Thacker, P. Ahrens, R. Chapin, A. Wasilk, E. A. Nelson. 1999. Detection of Mycoplasma hyopneumoniae by Nested PCR: A Comparison of Specimen Type and Extraction Methods. American Association of Veterinary Laboratory Diagnosticians. San Diego, CA.
95. Didion B. A,. S. T. Finn, M. Eisenhardt, J. Christopher-Hennings. 1999. Absence of Virus on Pig Embryos Recovered from Gilts Experimentally Infected with PRRSV. Abstract. National Animal Science Meeting. Indianapolis, IN.
96. Kaiser T. J., C. D. Nelson, J. P. Ledermann, E. A. Nelson, J. Christopher-Hennings. 1998. Measurement of Immunoglobulin A, G and M concentrations in boar semen. Abstract. Conference for Research Workers in Animal Diseases. Chicago, IL, P54.
97. Rossow K., E. Vaughn, E. A. Nelson, J. Christopher-Hennings, T. Fraser, W. Epperson, R. Rowland, S. Lawson, J. Stefanick, J. Kolb, P. Steen, D. Benfield. 1997. Investigation of an Abortion Storm in a RespPRRS Vaccinated Swine Herd from Southeast Iowa. Abstract. Allen D. Leman Swine Conference, Minneapolis, MN.
98. Benfield D. A., J. Christopher-Hennings, E. A. Nelson, R.R.R. Rowland, J. K. Nelson, C. C. L. Chase, K. D. Rossow and J. E. Collins. 1997. Persistent fetal infection of porcine reproductive and respiratory syndrome (PRRS) virus. American Association of Swine Practitioners. Quebec City, Canada.
99. Kaiser T. J., J. Christopher Hennings, C. D. Nelson, H. A. Jones, T. M. Weller, J. Neiger, D. A. Benfield, E. A. Nelson. 1997. Evaluation of Intranasal Vaccination for PRRSV in the Boar. Abstract. Conference for Research Workers In Animal Disease. Chicago, IL.
100. Nelson E. A., J. K. Nelson, L. P. Couture, M. L. Lau, J. Christopher-Hennings, C. C. L. Chase, R. A. Hesse. 1997. A Single Amino Acid Substitution Allows for the Differentiation of the Prime Pac PRRS Vaccine from Field Isolates of PRRSV. Abstract. Conference for Research Workers In Animal Diseases. Chicago, IL.
101. Nelson E. A., J. K. Nelson, C. C. L. Chase, J. Christopher-Hennings, L. P. Couture, M. L. Lau, R. A. Hesse. 1997. Differentiation of the Prime Pac PRRS Modified-Live Vaccine from Wild-Type PRRSV Isolates. Abstract. First International Veterinary Vaccines and Diagnostics Conference. Madison, WI.
102. Benfield D. A., J. Christopher-Hennings, E.A. Nelson, R. R. R. Rowland, C. C. L. Chase, J. K. Nelson, K. D Rossow. 1996. Current research on the effects of PRRSV in breeding age pigs. Abstract. Allen D. Leman Swine Conference. Minneapolis, MN.
103. Nelson E. A. J. K. Nelson, J. Christopher-Hennings, K.-J. Yoon, R. Magar and D. A. Benfield. 1996. Reactivity of North American PRRSV isolates with a monoclonal antibody panel. Abstract. 13th International Pig Veterinary Society Congress Proceedings, Bangkok, Thailand.
104. Christopher-Hennings J., E. A. Nelson, J. K. Nelson and D. A. Benfield. 1996. Evaluation of the RespPRRS modified-live PRRSV vaccine in adult boars. 13th International Pig Veterinary Society Congress Proceedings.
105. Rowland R. R. R., K. D. Rossow, J. E. Collins, J. Christopher-Hennings, E. A. Nelson and D. A. Benfield. 1996. Persistence of PRRS virus replication in lung and lymph nodes. Abstract, 11th Annual Meeting of the American Society for Virology.
106. Christopher-Hennings, J., E.A. Nelson, J. Nelson, K. Rossow, R. Rowland, M. Yaeger, C. Chase and D. Benfield. 1996. Identification of PRRSV in semen and tissue of vasectomized and non-vasectomized boars. 77th Conference of Research Workers in Animal Disease.
107. Wills, R., J. Zimmerman, K.-J. Yoon, S. Swenson, M. McGinley, H. Hill, K. Platt, J. Christopher-Hennings and E. Nelson. 1996. Porcine reproductive and respiratory syndrome virus - a persistent infection. Second International PRRS Symposium. Copenhagen, Denmark.
108. Benfield D.A., J. Christopher-Hennings, E. A. Nelson, M. Yaeger and C. C. L. Chase. 1996. Porcine reproductive and respiratory syndrome virus infections in the boar. Proceedings of The American Association of Swine Practitioners. pp. 581-584.
109. Nelson E. A., J. K. Nelson, J. Christopher-Hennings, P. Steen, K.-J. Yoon, R. Hesse, C. Chae and D. A. Benfield. 1995. Reactivity of PRRSV field isolates with a panel of monoclonal antibodies. Abstract, 76th Conference of Research Workers in Animal Diseases. Chicago, IL.
110. Christopher-Hennings J., E.A. Nelson, J. K. Nelson and D. A. Benfield. 1995. Evaluation of a modified-live PRRSV vaccine in adult boars. Abstract, 76th Conference of Research Workers in Animal Diseases. Chicago, IL.
111. Rowland R. R. R., K. D. Rossow, J. E. Collins, J. Christopher-Hennings, E. A. Nelson, and D. A. Benfield. 1995. Localization of PRRSV replication in the lung and other tissues using in situ hybridization. Abstract, 76th Conference of Research Workers in Animal Diseases. Chicago, IL.
112. Hurley D. J. R. R. R. Rowland, E. A. Nelson, J. Christopher-Hennings and D. A. Benfield. 1995. In vitro evidence that the PRRS virus interferes with normal lymphocyte activation. Abstract, 76th Conference of Research Workers in Animal Diseases. Chicago, IL.
113. Christopher-Hennings, J., E. A. Nelson, J. K. Nelson, S. Swenson, J. Zimmerman, J. Katz, M. Yaeger, C. Chase and D. A. Benfield. 1995. Persistent shedding of PRRSV in boar semen. Abstract, Second International PRRS Symposium. Copenhagen, Denmark.
114. Christopher-Hennings, J., E. A. Nelson, J. K. Nelson, R. J. Hines, S. L. Swenson, H. T. Hill, J. J. Zimmerman, M. J. Yaeger, C. C. L. Chase and D. A. Benfield. 1995. Persistence of PRRSV in boar serum and semen. American Society for Virology. Austin, TX.
115. Rossow K., J. Collins, S. Goyal, J. Hennings, E. A. Nelson and D. A. Benfield. 1995. The pathogenesis of porcine reproductive and respiratory syndrome virus in gnotobiotic pigs. Abstract, American Society of Veterinary Clinical Pathologists.
116. Rossow, K.D., J.E. Collins, S.M. Goyal, E.A. Nelson, J. Christopher-Hennings and D.A. Benfield. 1995. Chronological immunohistochemical detection and localization of porcine reproductive and respiratory syndrome virus in gnotobiotic pigs. American Association of Veterinary Laboratory Diagnosticians.
117. Yaeger, M.F., J. Christopher-Hennings, E.A. Nelson, J.K. Nelson, B.J. Hines, S.L. Swenson, H.T. Hill, J. Zimmerman, J.B. Katz, C.C.L. Chase and D.A. Benfield. 1995. PRRSV shedding in the semen of experimentally and naturally infected boars as detected by PCR. American Association of Veterinary Laboratory Diagnosticians.
118. Benfield, D.A., J. Christopher-Hennings, E.A. Nelson, J.K. Nelson, M.J. Yaeger, C.C.L. Chase, S.L. Swenson and J.Zimmerman. 1995. Acute and chronic porcine reproductive and respiratory syndrome virus infections in the boar. 36th George A. Young Swine Conference.
119. Christopher-Hennings, J., E. A. Nelson, J. K. Nelson, B. J. Hines, C. C. L. Chase, M. J. Yaeger, S. L. Swenson, J. Zimmerman, H. T. Hill, J. B. Katz, D.A. Benfield. 1994. Detection of porcine reproductive and respiratory syndrome virus in boar semen using the polymerase chain reaction. Abstract, 75th Conference of Research Workers in Animal Disease. Chicago, IL.
120. Nelson, E.A., J. Christopher-Hennings and D.A. Benfield. 1994. Structural proteins of porcine reproductive and respiratory syndrome virus. 6th International Symposium on Corona and Related Viruses, Quebec, Canada.
121. Christopher-Hennings, J., E. A. Nelson, R. J. Hines, J. K. Nelson, C. C. L. Chase, D. A. Benfield, M. J. Yaeger. 1994. Shedding of porcine reproductive and respiratory syndrome virus in the semen of experimentally infected boars. Abstract, 75th Conference of Research Workers in Animal Disease. Chicago, IL.
122. Nelson, E. A., J. Christopher-Hennings, A. K. Erickson, B. J. Hines, D. A. Benfield. 1994. Porcine reproductive and respiratory syndrome virus proteins. Abstract, 75th Conference of Research Workers in Animal Disease. Chicago, IL.
123. Benfield, D.A., E.A. Nelson and J. Christopher-Hennings. 1994. Porcine reproductive and respiratory syndrome (PRRS) viral proteins and antigenic variation. 13th International Pig Veterinary Society Congress Proceedings, Bankok, Thailand.
124. Chae, C., R. A. Moxley, J. Christopher-Hennings, D. H. Francis, and M. J. Wannemuehler. 1994. Shiga-like Toxin-II-Producing Escherichia coli 0157:H7 Infection in Gnotobiotic Piglets: Protection against Brain Vascular Lesions with SLT-II Antiserum. Abstract, 2nd International Symposium and Workshop on "Verotoxin (Shiga-like toxin)-Producing Escherichia coli Infections", Bergamo, Italy.
125. Nelson, E. A., J. Christopher-Hennings, G. Wensvoort, J. E. Collins, and D. A. Benfield. 1993. Differentiation of United States and European isolates of porcine reproductive and respiratory syndrome (PRRS) virus using monoclonal antibodies. Abstract, 74th Conference of Research Workers in Animal Disease. Chicago, IL.
126. Benfield, D.A., E.A. Nelson, J. Hennings, M. Minehart, D. Hurley and P. Steen. 1993. Update on porcine reproductive and respiratory syndrome (PRRS) virus and diagnosis. Livestock Conservation Institute Meeting.
127. Christopher-Hennings, J., E. A. Nelson, and D. A. Benfield. 1992. Evaluation of the antibody response to porcine respiratory and reproductive syndrome (PRRS) virus by indirect immunofluorescence (IFA), virus neutralization (VN), and immunoblotting. Abstract, 73rd Conference of Research Workers in Animal Disease. Chicago, IL.
128. Benfield D.A., L. Harris, E.A. Nelson, J.E. Collins, J.C. Hennings, D.W. Chladek, W. Christianson, R. Morrison and D. Gorcyca. 1992. A review of the etiology of swine infertility and respiratory syndrome (SIRS) or mystery swine disease and characteristics of SIRS virus (ATCC VR-2332) isolated in the United States. Mystery Swine Disease Committee Meeting, 1992 Livestock Conservation Institute Meeting.Nelson, E. A., J. Christopher-Hennings, and D. A. Benfield. 1992. Characterization and diagnostic use of monoclonal antibodies to U.S. isolates of porcine reproductive and respiratory syndrome (PRRS) virus. Abstract, 73rd Conference of Research Workers in Animal Disease. Chicago, IL.
129. Nelson E. A., J. Christopher-Hennings, L. Harris, J. E. Collins, D. W. Chladek, D. Gorcyca, D. A. Benfield. 1992. Preliminary characterization of monoclonal antibodies to a United States isolate (ATCC VR-2332) of porcine epidemic abortion and respiratory syndrome virus. 12th Congress. International Pig Veterinary Society. The Hague, The Netherlands and International Symposium on Swine Infertility and respiratory syndrome, St. Paul, MN.
130. Benfield, D., L. Harris, E. Nelson, J. Christopher-Hennings, J. Collins, D. Chladek, W. Christianson, R. Morrison, and D. Gorcyca. 1992. Properties of SIRS virus isolate ATCC VR-2332 in the United States and preliminary characterization of a monoclonal antibody to this virus. American Assoc. Swine Practitioners, International PRRS Symposium Edition, 4:19-21.
131. Chae, C., R. A. Moxley, J. Christopher-Hennings, D. H. Francis, M. Wannemuehler. 1992. Shiga-like toxin II producing Escherichia coli 0157:H7 infection in gnotobiotic piglets: protection against brain vascular lesions with anti-SLT-II serum. Abstract, 73rd Conference of Research Workers in Animal Disease. Chicago, IL.
132. Collins, J. E., D.A. Benfield, E. A. Nelson, W.T. Christianson, L. Harris, D. P. Shaw, J. Christopher-Hennings, S. M. Goyal, D. Gorcyca, R.B. Morrison, D. Chladek. 1992. Swine Infertility and respiratory syndrome (SIRS) in North America: Experimental reproduction and characterization of SIRS virus (isolate ATCC-VR2332). Abstract, VIth International Symposium, World Association of Veterinary Laboratory Diagnosticians.
133. Christopher-Hennings, J., Willgohs, J.A., Francis, D.H. Raman, U.A.K., Hurley, D.J. 1991. Immunosuppression in gnotobiotic piglets caused by verotoxin producing Escherichia coli (0111:NM). 72nd Conference of Research Workers in Animal Disease. Chicago, IL.
134. Hurley, D.J., Raman, U.A.K., Christopher-Hennings J., 1991. Immunosuppression observed in gnotobiotic piglets during infection with verotoxin producing E. coli (0111:NM) is caused by the superantigen activity of Shiga-like toxin I. South Dakota Academy of Sciences, Vermillion, SD.
135. Faulstich, C.S., Hildreth, M.B., Christopher-Hennings, J., Zeman, D.H., Francis, D.H. 1991. Preliminary effects of combined Escherichia coli and Isospora suis infection in gnotobiotic pigs. South Dakota Academy of Sciences, Vermillion, SD.

Work Experience

August 2013 to present Head, South Dakota State University Veterinary and Biomedical Sciences Department
August 2013 to present Director, South Dakota Animal Disease Research and Diagnostic Laboratory
June 2007 to present Professor, South Dakota State University
June 2000 to 2007: Associate Professor, South Dakota State University
January 1996-June 2000: Assistant Professor, South Dakota State University
1990-1995: Post-doctoral Research Associate, South Dakota State University,
1989-1990: Research Associate (Master’s Degree),
University of Wisconsin, Madison
1983-1989: Private Veterinary Practice, Rapid City, South Dakota

Grants

Funded Grant Proposals

1. Diel, D. , J. Christopher-Hennings, R. Rauh, J. Callahan , F. Li , T. Clement S. Lawson , E.A. Nelson . Development of multiplex real-time PCR and antibody reagents for the detection of swine acute diarrhea syndrome coronavirus (SADS-CoV). Sponsored by Swine Health Information Center. (July 1, 2018 to June 30, 2019).

2. Diel, D. , Nelson, E. , Christopher-Hennings, J. , Lawson, S., "Improved Strategies for Prevention and Control of Viral Diseases of Livestock.," Sponsored by USDA, Federal, Funded. (October 26, 2014 - October 30, 2019).

3. Diel, D., T. Clement, P. Leslie-Steen, J. Christopher-Hennings, E.A. Nelson. Genetic and biological characterization of PRRSV 1-7-4. National Pork Board. 9/16 to 3/18.
4. Lawson, S., D. Diel, Singrey, T. Clement, J. Christopher-Hennings, E.A. Nelson. Development of a bELISA for serological diagnostics and surveillance of Senecavirus A infection. National Pork Board. 5/17 to 6/18.

5. Scaria, J , Christopher-Hennings, J. , Nelson, E. A , "Development of direct fed microbial to reduce Salmonella colonization in beef cattle and to improve pre-harvest food safety," Sponsored by SD Beef Industry Council, 10/17 to 9/18.

6. Christopher-Hennings J., E.A. Nelson, J. Scaria, D. Diel, D. Wang, S. Herrmann, K. Kattelmann, V. Huber, M. Chaussee, F. Li. South Dakota Center for Biologics Research and Commercialization. SD Governor’s Office of Economic Development. 7/17-6/22.

7. Li, F., T. Clement, J. Christopher-Hennings, E.A. Nelson, R. Rauh, B. Hause. Detection and differentiation of influenza Types A, B, C and D in swine. Swine Health Information Center. 11/16 to 11/17.

8. Diel, D., T. Clement, S. Lawson, F. Bauermann, J. Christopher-Hennings, E.A. Nelson, R. Rauh. Development of rapid diagnostic capability for encephalomyocarditis virus. Swine Health Information Center. 11/16 to 11/17.

9. Christopher-Hennings, J., M. Chaussee, D. Diel, S. Herrmann, F. Li, E. Nelson, J. Scaria, K. Kattelmann, D. Wang. South Dakota Center for Biologics Research-Planning Grant. South Dakota Governor’s Office of Economic Development. 7/16 to 6/17.

10. Lawson, S., A. Singrey, T. Clement, D. Diel, J. Christopher-Hennings, E.A. Nelson. Development of reagents and serological assays for Seneca Valley Virus. Swine Health Information Center. 10/15 to 4/16.

11. Diel, D., T. Clement, E.A. Nelson, J. Christopher-Hennings, L. Caron, R. Shaefer. Characterization of Seneca Valley Virus circulating in the U.S. and Brazil. Swine Health Information Center. 10/15 to 4/16.

12. Diel. D., E.A. Nelson, J. Hennings, A. Pillatzki. Development of a multivalent vector platform to control swine enteric coronavirus disease. National Pork Board. 4/15 to 4/16.

13. Eric A. Nelson, Aaron Singrey, Steven Lawson, Travis Clement and J Christopher-Hennings. PEDV diagnostic approaches to assess sow immunity and piglet protection. National Pork Board General RFP, 5/1/14 to 4/30/15.

14. Dee, S., E. Nelson, D. Diel, T. Clement, A. Singrey, J. Hennings. An evaluation of a shipping model to investigate foreign animal disease introduction into the USA. American Association of Swine Veterinarians. 3/16 to 2/17.

15. Thaler, B., C. Lavesque, J Christopher-Hennings, E. Nelson, J. Clapper. Efficacy of soybean meal in reducing the effect of a PRRSV challenge in pigs. South Dakota Soybean and Promotion Council FY15. July 2014-July 2015.

16. Nelson, E.A., S. Lawson, A. Singrey, T. Clement, J. Christopher-Hennings. Development of reagents and serological assays for Porcine Deltacoronavirus (PDCoV). National Pork Board.

17. Diel, D., H. Vu, F. Osorio, E.A. Nelson, J Christopher-Hennings. Evaluation of immunodominant B- and T-cell epitopes as inducers of protective immunity against porcine reproductive and respiratory syndrome virus. National Pork Board.. Submitted 5-21-14. Oct. 1, 2014-Sept. 31, 2015.

18. Diel. D., E.A. Nelson, J. Hennings, A. Pillatzki. A novel platform for the development of live attenuated vaccine candidates for porcine epidemic diarrhea virus. National Pork Board. (year 1). Submitted Nov. 17, 2014.

19. Diel. D., E.A. Nelson, J. Hennings, A. Pillatzki. Development of a multivalent vector platform to control swine enteric coronavirus disease. National Pork Board. Submitted Nov. 17, 2014.

20. Christopher-Hennings J, B Thaler, E VanDerSluis. 2013. Honor’s Colloquium 303 on One Health" Achieving human, animal, agronomic, environmental and economic global well being" Honors in Agriculture Mini-Grant, South Dakota State University.

21. Christopher-Hennings J 2012. Diagnostic surveillance for unknown or incompletely defined pathogens through the Animal Disease Research and Diagnostic Laboratory, Veterinary and Biomedical Sciences Department, South Dakota State University. Department of Homeland Security and Center of Excellence for Emerging and Zoonotic Diseases (CEEZAD). September 2012-2013.

22. Christopher-Hennings J., B Thaler, E VanDerSluis. 2012. Honor’s Colloquium 303 on Agriculture and Global Health. Honors in Agriculture Mini-Grant, South Dakota State University.

23. Laegreid W., F. Osorio, T. Goldberg, J. Christopher-Hennings, E. Nelson. Immunological consequences of PRRSV Diversity. USDA-NRI, PRRSV CAP2. 2009-2013.

24. Zimmerman J, Y Fang, J Christopher-Hennings, E Nelson, T Opriessnig, R Rowland, K-J Yoon. 2012. Generating swine influenza virus (SIV) oral fluid diagnostic Reference Standards for community use. National Pork Board.

25. Fang Y., W. Zhang, J. Christopher-Hennings, E.A. Nelson and R.B. Baker. 2012. Development of an epitope-based vaccine against swine influenza A using a non-toxic enterotoxin as the carrier-adjuvant. National Pork Board.

26. Nelson, E.A., J. Christopher-Hennings, Y. Fang. 2012. Improved methods for the diagnosis of Porcine Reproductive and Respiratory Syndrome and other important viral diseases of swine. USDA Hatch.

27. Christopher-Hennings J, E Nelson, Y Fang, G Erickson, V Huber, H Harris. 2011. An alternative to hemagglutination inhibition (HI) assays for the simultaneous detection of multiple swine influenza subtype antibodies. Animal Disease Research and Diagnostic Laboratory, Veterinary and Biomedical Sciences Department.

28. Fang Y, J Zimmerman, C Irwin, J Christopher-Hennings, E Nelson. 2011. Novel multiplex diagnostic assays development for diagnosis of porcine respiratory disease complex. National Pork Board.

29. Reicks D, J Christopher-Hennings, E Nelson. 2011. The effect of PRRSV MLV vaccine given by exposure to vaccine saturated ropes. Annual Advancement in PRRSV Research Award, Boehringer-Ingelheim Animal Health 2011.

30. Christopher-Hennings J. International Planet xMAP Conference Presentation Travel Grant, Vienna, Austria. “Prosperity Through Innovation” (Proof of Concept) Grant, U.S. Small Business Association, 2010.

31. Lunney J, Christopher-Hennings J, Nelson E, Steibel JP, Zimmerman. Comparison of early immune responses of pigs which are genetically PRRS resistant/tolerant using a swine-specific immune protein (cytokine) multiplex assay. National Pork Board. 2009-2010.

32. Fang Y, Christopher-Hennings J, Nelson E, Zimmerman J, Murtaugh M. Development of diagnostic assays for detecting PRRSV infection using oral fluid samples as an alternative to serum-based assays. National Pork Board, 2009-2010.

33. Christopher-Hennings J., E. Nelson, Y, Fang, J. Lunney. Development of a rapid, swine-specific test to simultaneously detect multiple immune proteins (cytokines) affected by PRRSV infection. National Pork Board, submitted. $101,107.

34. Zhang, W., J. Christopher-Hennings. Pathogenesis of EAST1 toxin in ETEC associated diarrhea disease. NIH R15, 9-1-2009 to 8-31-2011.

35. Christopher-Hennings J., Y. Fang, E.A. Nelson. Elimination of Porcine Reproductive and Respiratory Syndrome Virus from semen: “On Farm” Mechanical and Antiviral Methods. 2007-2008.

36. Christopher-Hennings J., Acquisition of the Bio-Plex suspension Array system for multiplex assay development in swine research. Mucosal immunity to porcine reproductive and respiratory syndrome virus in the boar reproductive tract. USDA-NRI Equipment Grant.

37. Faaberg K., J. Christopher-Hennings, J. Collins, E. Retzel. Implementation of a PRRSV database-Renewal. National Pork Board. 2006-2007.

38. Christopher-Hennings J. C. Munoz-Zanzi, N. Loskutoff, J. Lunney, E. Nelson. PRRSV surveillance, elimination and immunity in boars and boar semen. USDA-NRI Integrated Program. April 2006—January 2008.

39. Nelson E.A., R.R.R. Rowland, J. Christopher-Hennings. Emerging European-like PRRSV in the U.S.: Implications for diagnostic and control strategies. National Pork Board. Jan 2005-Jan 2006.

40. Fang Y., D Benfield, R. R. R. Rowland, J. Christopher-Hennings, E.A. Nelson. Accurate ELISA test development for PRRSV serology: evaluation of cysteine protease domains of nsp2 as potential diagnostic targets. National Pork Board, Aug 2005-Aug 2006.

41. Wang X, W. Cafruny, Y. Fang, R. Kaushik, J. Christopher-Hennings, E.A. Nelson. Improved diagnostic and vaccination strategies for PRRSV. SD 2010 Program (CIDRV), Oct 2004-Oct 2006.

42. Rowland, R.R., J. Zimmerman, R. Evans, J. Christopher-Hennings, E.A. Nelson and D.A. Benfield. Management of PRRS Persistence: Identification of persistently infected swine. USDA-NRI Integrated Program. Sept. 2004 to Sept. 2005. .

43. Wang, X., W. Bowers, E.A. Nelson and J. Christopher-Hennings. A Novel herpesvirus vector approach for PRRSV vaccines. National Pork Board. Sept. 2004 to Sept. 2005..

44. Murtaugh et. al. Integrated control and elimination of porcine reproductive and respiratory syndrome virus (PRRSV) in the U.S. USDA-NRI Integrated Program. March 2004-Dec 2007.

45. Christopher-Hennings J., E. A. Nelson. 2002-2004. Porcine Reproductive and Respiratory Syndrome Virus detection, protection and elimination of virus. Agriculture Experiment Station.

46. Christopher-Hennings J. E. A. Nelson. Detection, Predictors, Immune Mechanisms and Prevalence of PRRSV Persistence in Boars. Iowa Pork Producers Council. 2002. .

47. Christopher-Hennings J. E. A. Nelson. Development and validation of a real-time, quantitative PCR for the detection of PRRSV in boar semen and serum. PIC, Boehringer-Ingelheim Vetmedica, Tetracore, Inc. 2002-2003.

48. Christopher-Hennings J, E.A. Nelson, B. Epperson, C. Chase, D. Henning. Johne’s Disease in Cattle and Buffalo: A South Dakota Concern. Agricultural Experiment Station Cooperative Grants Program. 2000-2002.

49. Nelson E. A., M. Murtaugh, J. Christopher-Hennings. Evaluation of a blocking ELISA to verify suspect false positive PRRSV serology results. Pig Improvement Company (PIC-USA). November 1, 2000 to October 31, 2001.

50. Kuckleburg C, J Christopher-Hennings. Using PCR for the Early Detection of a Bovine Retrovirus in the Milk of Normal and Transgenic Cattle. South Dakota State University Research Support Fund. 1998-1999.

51. Christopher-Hennings J. E.A. Nelson. Breed and Litter Factors related to PRRSV Persistence and Clearance. National Pork Producers Council. 1999-2000. .

52. Christopher-Hennings J., E. A. Nelson, D. A. Benfield. Acquisition of an ABI PRISM 7700 Sequence Detection System. USDA, National Research Initiative Equipment Grant. September 1, 1998.

53. Rossow K. D., J. Christopher-Hennings, J. Collins, D. A. Benfield, E. A. Nelson, W. Epperson. Porcine reproductive and respiratory syndrome virus infection characterized by marked neurovirulence in neonatal pigs: fetal challenge in late-gestation sows. National Pork Producers Council. 1997.

54. Nelson E. A., J. Christopher-Hennings. Envelope proteins of PRRSV and their role in antigenic variation. USDA, National Research Initiative. October 1, 1996 to September 30, 1999.

55. Benfield D. A., R. R. Rowland, J. Christopher-Hennings, E. A. Nelson, J. K. Nelson: Development of a quantitative PCR to evaluate the risk of boar semen as a source of PRRS virus. National Pork Producers Council Grant, 1995 to 1998.

56. Christopher-Hennings, J., E. A. Nelson, D. A. Benfield. Evaluation of intranasal vaccination for PRRSV and the mucosal immune response in the boar. South Dakota Pork Producers Council. September 1996 to September 1997.

57. Christopher-Hennings J., E. A. Nelson, R. R. Rowland, D. A. Benfield: Evaluation of intranasal vaccination for PRRSV and the mucosal immune response in the boar. National Pork Producers Council Grant, 1995.

58. Nelson, E. A., D. A. Benfield, J. Christopher-Hennings, Christopher C. L. Chase: Development and evaluation of a blocking and/or competitive ELISA for the improved serodiagnosis of Porcine Reproductive and Respiratory Syndrome. National Pork Producers Council Research Proposal. July 1, 1995-June 30, 1996.

59. Benfield, D. A., J. Christopher-Hennings, E. A. Nelson: Use of a commercial Porcine Reproductive and Respiratory Syndrome virus vaccine (RespPRRS) to control PRRSV infection in boars. South Dakota Pork Producers Council Research Proposal. July 1, 1995-June 30, 1996.

60. Benfield, D. A., Christopher-Hennings J., E. A. Nelson, M. J. Yaeger, C. C. L. Chase: Development and evaluation of a polymerase chain reaction assay for detection of Porcine Reproductive and Respiratory Syndrome Virus in Boar Semen. South Dakota Pork Producers Council. August 1, 1994-July 31, 1995.

61. Christopher-Hennings J. and E. A. Nelson: Molecular Methods to Detect Porcine Reproductive and Respiratory Syndrome Virus in the Boar. USDA-National Competitive Research Initiative Grants Program, Seed Grant. October 1, 1994-September 31, 1996.

62. Holler, L. D., J. Christopher-Hennings, E. A. Nelson, M. J. Yaeger: Diagnosis and pathogenesis of Porcine Reproductive and Respiratory Syndrome Virus in the fetus and the reproductive tract of the sow using the polymerase chain reaction and immunohistochemistry. South Dakota Agricultural Experiment Station Grant. October 1, 1994-September 30, 1995. .

63. Yaeger, M. J., J. Christopher-Hennings, D. A. Benfield, C. C. L. Chase: The role of boar semen in the transmission of swine infertility and respiratory syndrome (SIRS). South Dakota Agricultural Experiment Station Grant. October 1, 1992-September 30, 1994.

64. Hurley, D. J. and J. Christopher-Hennings: Establishment of the effects of colostrally derived protein food supplements on human and animal health. Governor's office of economic development, through the Center for Innovation, Technology & Entrepreneurship (CITE). November 1992 to October 31, 1993.

Patents

Intellectual Property: License Agreements
1. Multiplex immune effector molecule assay—Swine cytokines. Developed by Christopher-Hennings, Lawson, Fang and Nelson.
2. Development of lateral flow pathogen detection assays using monoclonal antibodies against PRRSV and other viral pathogens. Tetracore, Inc. E.A. Nelson and J. Christopher-Hennings.
3. PRRSV real-time PCR with Tetracore, Inc., Rockville, NJ
4. Johne’s (Mycobacterium avium subsp paratuberculosis) real-time PCR with Tetracore. Inc., Rockville, NJ


Intellectual Property: Patent Applications
1. Multiplex immune effector molecule assay. J. Christopher-Hennings, S. Lawson, Y. Fang and E. Nelson. Licensed Technology with Life Technologies, Carlsbad, CA. Patent Pending (Application number PCT/US2011/039874).

2. Recombinant North American type 1 porcine reproductive and respiratory syndrome virus and methods of use. Fang, Y., E.A. Nelson and J. Christopher-Hennings. U.S. patent # 8182984. Issued May 22, 2012.

Awards & Honors

South Dakota State University, Dr. April Brooks Woman of Distinction Award- Administration Category, 2017.
Dean’s Team Award for Contributions to the Center for Infectious Disease Research and Vaccinology, 2005 (Governor’s 2010 Program).
Hanson Award. Individual award from the University of Minnesota for outstanding contributions in the swine industry, September 2002.

Research/Scholarship Responsibilities

PubMed Refereed Articles
1. Ghimire S., R. Kumar, E. Nelson, J. Christopher-Hennings, J. Scaria. Genome sequence and description of Blautia brookingsii str SG772 nov., a new species of anaerobic bacterium isolated from healthy human gut. bioRxiv preprint doi: https://doi.org/10.1101/327007
2. Bjustrom-Kraft J, Christopher-Hennings J, Daly R, Main R, Torrison J, Thurn M, Zimmerman J. The use of oral fluid diagnostics in swine medicine. J Swine Health and Production. 2018;26(5):262-269.
3. Dee S., F. Bauermann, M. Niederwerder, A. Singrey, T. Clement, M. deLima; C. Long, G. Patterson, M. Sheehan, A Stoian, V Petrovan, C. Jones, J. de Jong, J. Ji; G. Spronk; J. Christopher- Hennings, J. Zimmerman, B. Rowland; E. Nelson; P. Sundberg, D. Diel. 2018.
Survival of viral pathogens in animal feed ingredients under transboundary shipping models. PloS ONE. doi:10.1371/journal.pone.0194509. March 20, 2018.
4. Okda, F., S. Lawson, A. Singrey, J. Nelson, K.S Hain, L.R Joshi, J. Christopher-Hennings, E.A. Nelson, D. G. Diel. 2017. The S2 glycoprotein subunit of porcine epidemic diarrhea virus contains immunodominant neutralizing epitopes. Virology. 509:185-194.
5. Nedland H., J. Wollman, C. Sreenivasen, M. Quast, A. Singrey, L. Fawcett, J. Christopher-Hennings, E. Nelson, R. Kaushik, D. Wang, F. Li. 2018. Serological evidence for the co-circulation of two lineages of influenza D viruses in equine populations of the Midwest United States. Zoonosis Public Health 65:148-154.
6. Thomas M., M. Webb, S. Ghimire, A Blair, K Olson, G. Fenske, A Fonder, J. Christopher-Hennings, D. Brake, J Scaria. 2017. Metagenomic characterization of the effect of feed additives on the gut microbiome and antibiotic resistome of feedlot cattle. Scientific Reports. Submitted.
7. Bauermann F., L. Josh1, K. Mohr, G. Kutish, P. Meier, C. Chase, J. Christopher-Hennings, D. Diel. 2017. A novel bovine papillomavirus type in the genus Dyokappapapillomavirus
Archives of Virology. doi: 10.1007/s00705-017-3443-9. [Epub ahead of print]
8. Useh NM, Ngbede EO, Akange N, Thomas M, Foley A, Keena MC, Nelson E, Christopher-Hennings J, Tomita M, Suzuki H, Scaria J. Draft Genome Sequences of 37 Salmonella enterica Strains Isolated from Poultry Sources in Nigeria..Genome Announc. 2016 May 5;4(3). pii: e00315-16. doi: 10.1128/genomeA.00315-16.PMID:27151793
9. Diel, D.G., S. Lawson, F. Okda, A. Singrey, T. Clement, M.H.V. Fernandes, J. Christopher-Hennings, E.A. Nelson. 2016. Porcine epidemic diarrhea virus: an overview of current virological and serological diagnostic methods. Virus Research. doi.org/10.1016/j.virusres. 2016.05.013.
10. Goodell C, J Zhang, E Strait, K Harmon, D Patnayak, T Otterson, M Culhane, J Christopher-Hennings, T Clement, P Leslie-Steen, R Hesse,J Anderson, K Skarbek, A Vincent, P Kitikoon, S Swenson, M Jenkins-Moore, Ji McGill, R Rauh, W Nelson, C O’Connell, R Shah, C Wang, R Main, J Zimmerman 2016. Ring test evaluation of the detection of influenza A virus in swine oral fluids by real-time reverse-transcription polymerase chain reaction and virus isolation. Canadian Journal of Veterinary Research. 80:12-20.
11. Okda, F., S. Lawson, X. Liu, A. Singrey, T. Clement, J. Nelson, J. Christopher-Hennings, E.A. Nelson. 2016. Development of monoclonal antibodies and serological assays including indirect ELISA and fluorescent microsphere immunoassays for diagnosis of porcine deltacoronavirus. BMC Vet. Res. 12:95. doi: 10.1186/s12917-016-0716-6.
12. Quast M; Sreeniyasan C.; Sexton G, Hunter N, Singrey A, Fawcett L, Miller G, Lauer D, S Voss S, S Pollock, C Cunhad, J Christopher-Hennings, E Nelson, F Li. 2015. Serological evidence for the presence of influenza D virus in small ruminants. Veterinary Microbiology 180:281-285.
13. Clement, T; G Kutish, J Nezworski, J Scaria, Eric Nelson, J Christopher-Hennings, D Diel. 2015. Complete Genome Sequence of a Highly Pathogenic Avian Influenza Virus (H5N2) Associated with an Outbreak in Commercial Chickens, Iowa, USA, 2015. Genome announcements. 3:e00613,
14. Joshi, L., K. Mohr, T. Clement, K. Hain, B. Myers, J. Yaros, E. Nelson, J. Christopher-Hennings, D. Gava, R. Schaefer, L. Caron, S. Dee, D. Diel. 2016. Detection of the Newly Emerging Senecavirus A in Pigs, Mice and Houseflies. J Clin Micro. 54:1536-1545. doi: 10.1128/JCM.03390-15.
15. Dee, S., C. Neill, A. Singrey, T. Clement, R. Cochrane, C. Jones, G. Patterson, J. Christopher-Hennings, E. Nelson. 2016. Modeling the transboundary risk of feed ingredients contaminated with porcine epidemic diarrhea virus. BMC Vet. Res. 12:51.
16. Okda F., Liu X, Singrey A, Clement T, Nelson J, Christopher-Hennings J, Nelson EA, Lawson S. 2015. Development of an indirect ELISA, blocking ELISA, fluorescent microsphere immunoassay and fluorescent focus neutralization assay for serologic evaluation of exposure to North American strains of Porcine Epidemic Diarrhea Virus. BMC Veterinary Research 12:95
17. Sreenivasan C., S. Jandhyala, , S. Luo, B Hause, M. Thomas, D. Knudsen, P. Stein, T. Clement, S Reedy, T. Chambers, J. Christopher-Hennings, E. Nelson, D. Wang, R. Kaushik2, F. Li .2018. Phylogenetic analysis and characterization of a sporadic isolate of equine influenza A H3N8 from an unvaccinated horse in 2015. Viruses 10:31
18. Dee, S., C. Neill, T. Clement, A. Singrey, J. Hennings, E. Nelson. 2015. An evaluation of porcine epidemic diarrhea virus survival in individual feed ingredients in the presence or absence of a liquid antimicrobial. Porcine Health Management. 2015,1:9 doi:10.1186/s40813-015-0003-0..
19. Ran Z, H. Shen, Y. Lang, E. Kolb, N.i Turan, L. Zhu, J. Ma, B. Bawa, Q. Liu, H. Liu, M. Quast, G. Sexton, F.Krammer, B. Hause, J Christopher-Hennings, E. Nelson, J. Richt, F. Li, W. Ma. 2015. Domestic pigs are susceptible to infection with influenza B viruses. J. Virology 89:4818-4826..
20. Dee S, C Neill, T Clement, J Christopher-Hennings, E. Nelson. 2014. An evaluation of a liquid antimicrobial (Sal CURB®) for reducing the risk of porcine epidemic diarrhea virus infection of naïve pigs during consumption of contaminated feed. BMC Veterinary Research, 10:220.
21. Dee S, T. Clement, A. Schelkopf, J. Nerem, D. Knudsen, J Christopher-Hennings, E. Nelson. 2014. An evaluation of contaminated complete feed as a vehicle for porcine epidemic diarrhea virus infection of naïve pigs following consumption via natural feeding behavior: Proof of concept. BMC Veterinary Research, 10:176.
22. Christopher-Hennings J, K Araujo, Ying Fang, Steve Lawson, Eric Nelson, Joan Lunney. 2013. Considerations for performing Luminex multianalyte profiling (xMAP) in veterinary diagnostic laboratories. J Vet Diagn Invest 25,773.
23. Hanmo Zhang; Xueshui Guo; Eric Nelson; Jane Christopher-Hennings; Xiuqing Wang. Porcine reproductive and respiratory syndrome virus activates the transcription of interferon alpha/beta (IFN-α/β) in monocyte-derived dendritic cells (Mo-DC). Vet. Microbiol. 159, 494 (2012).
24. Tavis K Anderson; William W Laegreid; Francesco Cerutti; Fernando A Osorio; Eric A Nelson; Jane Christopher-Hennings; Tony L Goldberg. Ranking viruses: measures of positional importance within networks define core viruses for rational polyvalent vaccine development. Bioinformatics 28, 1624 (2012).
25. Xiuqing Wang; Jane Christopher-Hennings. Post-transcriptional control of type I interferon induction by porcine reproductive and respiratory syndrome virus in its natural host cells. Viruses 4, 725 (2012).
26. Robert J Langenhorst; Steven Lawson; Apisit Kittawornrat; Jeffrey J Zimmerman; Zhi Sun; Yanhua Li; Jane Christopher-Hennings; Eric A Nelson; Ying Fang et al. Development of a fluorescent microsphere immunoassay for detection of antibodies against porcine reproductive and respiratory syndrome virus using oral fluid samples as an alternative to serum-based assays. Clin. Vaccine Immunol. 19, 180 (2012).
27. Steven R Lawson; Yanhua Li; John B Patton; Robert J Langenhorst; Zhi Sun; Zhiyong Jiang; Jane Christopher-Hennings; Eric A Nelson; David Knudsen; Ying Fang. Interleukin-1β expression by a recombinant porcine reproductive and respiratory syndrome virus. Virus Res. 163, 461 (2012).
28. Steven Lawson; Joan Lunney; Federico Zuckermann; Fernando Osorio; Eric Nelson; Craig Welbon; Travis Clement; Ying Fang; Susan Wong; Karen Kulas; Jane Christopher-Hennings. Development of an 8-plex Luminex assay to detect swine cytokines for vaccine development: assessment of immunity after porcine reproductive and respiratory syndrome virus (PRRSV) vaccination. Vaccine 28, 5356 (2010).
29. Dan Wang; Aaron Harmon; Jing Jin; David H Francis; Jane Christopher-Hennings; Eric Nelson; Ronald C Montelaro; Feng Li. The lack of an inherent membrane targeting signal is responsible for the failure of the matrix (M1) protein of influenza A virus to bud into virus-like particles. J. Virol. 84, 4673 (2010)
30. Joan K Lunney; Eric R Fritz; James M Reecy; Daniel Kuhar; Elizabeth Prucnal; Ramon Molina; Jane Christopher-Hennings; Jeffrey Zimmerman; Raymond R R Rowland. Interleukin-8, interleukin-1beta, and interferon-gamma levels are linked to PRRS virus clearance. Viral Immunol. 23, 127 (2010).
31. Zhenhai Chen; Xiaoxin Zhou; Joan K Lunney; Steven Lawson; Zhi Sun; Elizabeth Brown; Jane Christopher-Hennings; David Knudsen; Eric Nelson; Ying Fang. Immunodominant epitopes in nsp2 of porcine reproductive and respiratory syndrome virus are dispensable for replication, but play an important role in modulation of the host immune response. J. Gen. Virol. 91, 1047 (2010).
32. Z Chen; S Lawson; Z Sun; X Zhou; X Guan; J Christopher-Hennings; E A Nelson; Y Fang. Identification of two auto-cleavage products of nonstructural protein 1 (nsp1) in porcine reproductive and respiratory syndrome virus infected cells: nsp1 function as interferon antagonist. Virology 398, 87 (2010).
33. R M Molina; E A Nelson; J Christopher-Hennings; R Hesse; R R R Rowland; J J Zimmerman. Evaluation of the risk of PRRSV transmission via ingestion of muscle from persistently infected pigs. Transbound Emerg Dis 56, 1 (2009).
34. Michael S Kinch; Abdul S Yunus; Calli Lear; Hanwen Mao; Hanson Chen; Zena Fesseha; Guangxiang Luo; Eric A Nelson; Limin Li; Zhuhui Huang; M. Mury; W. Y. Ellis, L. Hensley, J. Christopher-Hennings; G. G. Olinger, M. Goldblatt. FGI-104: a broad-spectrum small molecule inhibitor of viral infection. Am J Transl Res 1, 87 (2009).
35. R M Molina; S-H Cha; W Chittick; S Lawson; M P Murtaugh; E A Nelson; J Christopher-Hennings; K-J Yoon; R Evans; R R R Rowland; et al. Immune response against porcine reproductive and respiratory syndrome virus during acute and chronic infection. Vet. Immunol. Immunopathol. 126, 283 (2008).
36. Ying Fang; Jane Christopher-Hennings; Elizabeth Brown; Haixia Liu; Zhenhai Chen; Steven R Lawson; Rachael Breen; Travis Clement; Xiaofei Gao; Jingjing Bao; et al. Development of genetic markers in the non-structural protein 2 region of a US type 1 porcine reproductive and respiratory syndrome virus: implications for future recombinant marker vaccine development. J. Gen. Virol. 89, 3086 (2008).
37. Ramon M Molina; Wayne Chittick; Eric A Nelson; Jane Christopher-Hennings; Raymond R R Rowland; Jeffrey J Zimmerman. Diagnostic performance of assays for the detection of anti-Porcine reproductive and respiratory syndrome virus antibodies in serum and muscle transudate ("meat juice") based on samples collected under experimental conditions. J. Vet. Diagn. Invest. 20, 735 (2008).
38. Erin L Strait; Melissa L Madsen; F Chris Minion; Jane Christopher-Hennings; Matthew Dammen; Katherine R Jones; Eileen L Thacker. Real-time PCR assays to address genetic diversity among strains of Mycoplasma hyopneumoniae. J. Clin. Microbiol. 46, 2491 (2008).
39. Jane Christopher-Hennings; Eric A Nelson; Gary C Althouse; Joan Lunney. Comparative antiviral and proviral factors in semen and vaccines for preventing viral dissemination from the male reproductive tract and semen. Anim Health Res Rev 9, 59 (2008).
40. John Prickett; Robert Simer; Jane Christopher-Hennings; Kyoung-Jin Yoon; Richard B Evans; Jeffrey J Zimmerman. Detection of Porcine reproductive and respiratory syndrome virus infection in porcine oral fluid samples: a longitudinal study under experimental conditions. J. Vet. Diagn. Invest. 20, 156 (2008).
41. Diane R Baker; Rodney A Moxley; Mike B Steele; Jeffrey T Lejeune; Jane Christopher-Hennings; Ding-Geng Chen; Philip R Hardwidge; David H Francis. Differences in virulence among Escherichia coli O157:H7 strains isolated from humans during disease outbreaks and from healthy cattle. Appl. Environ. Microbiol. 73, 7338 (2007).
42. Albert Rovira; Travis Clement; Jane Christopher-Hennings; Bob Thompson; Mark Engle; Darwin Reicks; Claudia Muñoz-Zanzi. Evaluation of the sensitivity of reverse-transcription polymerase chain reaction to detect porcine reproductive and respiratory syndrome virus on individual and pooled samples from boars. J. Vet. Diagn. Invest. 19, 502 (2007).
43. Federico A Zuckermann; Esther Alvarez Garcia; Ivan Diaz Luque; Jane Christopher-Hennings; Alan Doster; Monica Brito; Fernando Osorio. Assessment of the efficacy of commercial porcine reproductive and respiratory syndrome virus (PRRSV) vaccines based on measurement of serologic response, frequency of gamma-IFN-producing cells and virological parameters of protection upon challenge. Vet. Microbiol. 123, 69 (2007).
44. X Wang; M Eaton; M Mayer; H Li; D He; E Nelson; J Christopher-Hennings. Porcine reproductive and respiratory syndrome virus productively infects monocyte-derived dendritic cells and compromises their antigen-presenting ability. Arch. Virol. 152, 289 (2007).
45. Ying Fang; Raymond R R Rowland; Michael Roof; Joan K Lunney; Jane Christopher-Hennings; Eric A Nelson. A full-length cDNA infectious clone of North American type 1 porcine reproductive and respiratory syndrome virus: expression of green fluorescent protein in the Nsp2 region. J. Virol. 80, 11447 (2006).
46. Jane Christopher-Hennings; Matthew Dammen; Eric Nelson; Raymond Rowland; Richard Oberst. Comparison of RNA extraction methods for the detection of porcine reproductive and respiratory syndrome virus from boar semen. J. Virol. Methods 136, 248 (2006).
47. Ying Fang; Kay S Faaberg; Raymond R R Rowland; J Christopher-Hennings; Asit K Pattnaik; Fernando Osorio; Eric A Nelson. Construction of a full-length cDNA infectious clone of a European-like Type 1 PRRSV isolated in the U.S. Adv. Exp. Med. Biol. 581, 605 (2006).
48. Wai-Hong Wu; Ying Fang; Raymond R R Rowland; Steven R Lawson; Jane Christopher-Hennings; Kyoung-Jin Yoon; Eric A Nelson. The 2b protein as a minor structural component of PRRSV. Virus Res. 114, 177 (2005).
49. Wesley Johnson; Michael Roof; Eric Vaughn; Jane Christopher-Hennings; Craig R Johnson; Michael P Murtaugh. Pathogenic and humoral immune responses to porcine reproductive and respiratory syndrome virus (PRRSV) are related to viral load in acute infection. Vet. Immunol. Immunopathol. 102, 233 (2004).
50. A Wasilk; J D Callahan; J Christopher-Hennings; T A Gay; Y Fang; M Dammen; M E Reos; M Torremorell; D Polson; M Mellencamp; et al. Detection of U.S., Lelystad, and European-like porcine reproductive and respiratory syndrome viruses and relative quantitation in boar semen and serum samples by real-time PCR. J. Clin. Microbiol. 42, 4453 (2004).
51. Susan L Ropp; Carrie E Mahlum Wees; Ying Fang; Eric A Nelson; Kurt D Rossow; Melissa Bien; Bill Arndt; Sarah Preszler; Pamela Steen; Jane Christopher-Hennings; et al. Characterization of emerging European-like porcine reproductive and respiratory syndrome virus isolates in the United States. J. Virol. 78, 3684 (2004).
52. Ying Fang; Dal-Young Kim; Susan Ropp; Pam Steen; Jane Christopher-Hennings; Eric A Nelson; Raymond R R Rowland. Heterogeneity in Nsp2 of European-like porcine reproductive and respiratory syndrome viruses isolated in the United States. Virus Res. 100, 229 (2004).
53. Jane Christopher-Hennings; Matthew A Dammen; Shelleen R Weeks; William B Epperson; Shri N Singh; Gina L Steinlicht; Ying Fang; Jessica L Skaare; Jill L Larsen; Janet B Payeur; et al. Comparison of two DNA extractions and nested PCR, real-time PCR, a new commercial PCR assay, and bacterial culture for detection of Mycobacterium avium subsp. paratuberculosis in bovine feces. J. Vet. Diagn. Invest. 15, 87 (2003).
54. Christopher J Kuckleburg; Christopher C Chase; Eric A Nelson; Salvatore A E Marras; Matthew A Dammen; Jane Christopher-Hennings. Detection of bovine leukemia virus in blood and milk by nested and real-time polymerase chain reactions. J. Vet. Diagn. Invest. 15, 72 (2003).
55. James E Benson; Michael J Yaeger; Jane Christopher-Hennings; Kelly Lager; Kyoung-Jin Yoon. A comparison of virus isolation, immunohistochemistry, fetal serology, and reverse-transcription polymerase chain reaction assay for the identification of porcine reproductive and respiratory syndrome virus transplacental infection in the fetus. J. Vet. Diagn. Invest. 14, 8 (2002).
56. Ying Fang; Wai-Hong Wu; Jessica L Pepper; Jill L Larsen; Salvatore A E Marras; Eric A Nelson; William B Epperson; Jane Christopher-Hennings. Comparison of real-time, quantitative PCR with molecular beacons to nested PCR and culture methods for detection of Mycobacterium avium subsp. paratuberculosis in bovine fecal samples. J. Clin. Microbiol. 40, 287 (2002).
57. W H Wu; Y Fang; R Farwell; M Steffen-Bien; R R Rowland; J Christopher-Hennings; E A Nelson. A 10-kDa structural protein of porcine reproductive and respiratory syndrome virus encoded by ORF2b. Virology 287, 183 (2001).
58. J Christopher-Hennings; L D Holler; D A Benfield; E A Nelson. Detection and duration of porcine reproductive and respiratory syndrome virus in semen, serum, peripheral blood mononuclear cells, and tissues from Yorkshire, Hampshire, and Landrace boars. J. Vet. Diagn. Invest. 13, 133 (2001).
59. T J Kaiser; J Christopher-Hennings; E A Nelson. Measurement of immunoglobulin G, A and M concentrations in boar seminal plasma. Theriogenology 54, 1171 (2000).
60. J Christopher-Hennings; E A Nelson; J K Nelson; K D Rossow; J L Shivers; M J Yaeger; C C Chase; R A Garduno; J E Collins; D A Benfield. Identification of porcine reproductive and respiratory syndrome virus in semen and tissues from vasectomized and nonvasectomized boars. Vet. Pathol. 35, 260 (1998).
61. J Christopher-Hennings; E A Nelson. PCR analysis for the identification of porcine reproductive and respiratory syndrome virus in boar semen. Methods Mol. Biol. 92, 81 (1998).
62. R W Wills; J J Zimmerman; K J Yoon; S L Swenson; M J McGinley; H T Hill; K B Platt; J Christopher-Hennings; E A Nelson. Porcine reproductive and respiratory syndrome virus: a persistent infection. Vet. Microbiol. 55, 231 (1997).
63. J Christopher-Hennings; E A Nelson; J K Nelson; D A Benfield. Effects of a modified-live virus vaccine against porcine reproductive and respiratory syndrome in boars. Am. J. Vet. Res. 58, 40 (1997).
64. K D Rossow; D A Benfield; S M Goyal; E A Nelson; J Christopher-Hennings; J E Collins. Chronological immunohistochemical detection and localization of porcine reproductive and respiratory syndrome virus in gnotobiotic pigs. Vet. Pathol. 33, 551 (1996).
65. J Christopher-Hennings; E A Nelson; R J Hines; J K Nelson; S L Swenson; J J Zimmerman; C L Chase; M J Yaeger; D A Benfield. Persistence of porcine reproductive and respiratory syndrome virus in serum and semen of adult boars. J. Vet. Diagn. Invest. 7, 456 (1995).
66. J Christopher-Hennings; I D Kurzman; A L Haffa; J W Kemnitz; E G Macewen. The effect of high fat diet and dehydroepiandrosterone (DHEA) administration in the rhesus monkey. In Vivo 9, 415 (1995).
67. R Magar; R Larochelle; S Dea; C A Gagnon; E A Nelson; J Christopher-Hennings; D A Benfield. Antigenic comparison of Canadian and US isolates of porcine reproductive and respiratory syndrome virus using monoclonal antibodies to the nucleocapsid protein. Can. J. Vet. Res. 59, 232 (1995).
68. J Christopher-Hennings; E A Nelson; J K Nelson; R J Hines; S L Swenson; H T Hill; J J Zimmerman; J B Katz; M J Yaeger; C C Chase. Detection of porcine reproductive and respiratory syndrome virus in boar semen by PCR. J. Clin. Microbiol. 33, 1730 (1995).
69. K D Rossow; J E Collins; S M Goyal; E A Nelson; J Christopher-Hennings; D A Benfield. Pathogenesis of porcine reproductive and respiratory syndrome virus infection in gnotobiotic pigs. Vet. Pathol. 32, 361 (1995).
70. E A Nelson; J Christopher-Hennings; D A Benfield. Structural proteins of porcine reproductive and respiratory syndrome virus (PRRSV). Adv. Exp. Med. Biol. 380, 321 (1995).
71. E A Nelson; J Christopher-Hennings; D A Benfield. Serum immune responses to the proteins of porcine reproductive and respiratory syndrome (PRRS) virus. J. Vet. Diagn. Invest. 6, 410 (1994).
72. E A Nelson; J Christopher-Hennings; T Drew; G Wensvoort; J E Collins; D A Benfield. Differentiation of U.S. and European isolates of porcine reproductive and respiratory syndrome virus by monoclonal antibodies. J. Clin. Microbiol. 31, 3184 (1993).
73. J Christopher-Hennings; J A Willgohs; D H Francis; U A Raman; R A Moxley; D J Hurley. Immunocompromise in gnotobiotic pigs induced by verotoxin-producing Escherichia coli (O111:NM). Infect. Immun. 61, 2304 (1993).

Non-PubMed Publications
1. Clement, T., A. Singrey, S. Lawson, F. Okda, J. Nelson, D. Diel, E.A. Nelson, J. Christopher-Hennings. 2016. Quantitation of porcine epidemic diarrhea virus neutralizing antibodies in sow serum, colostrum, milk and piglet serum after feedback. J. Swine Health and Production 24:147-153.
2. Stricker A. D Polson, M Murtaugh.; et Variation in porcine reproductive and respiratory syndrome virus open reading frame 5 diagnostic sequencing. 2015. Swine Health and Production 23:18-27.
3. National Hog Farmer, Biofilters can reduce spread of PRRS virus, Nicolai, D., E.A. Nelson, J. Christopher-Hennings, B. Thaler and S. Pohl. Dec. 15, 2009. P. 23-25.
4. Reicks DL, C. Muñoz-Zanzi, W. Mengeling J. Christopher-Hennings, K. Lager, D. Polson, S. Dee, K. Rossow. 2006. Detection of porcine reproductive and respiratory syndrome virus in semen and serum of boars during the first six days after inoculation. Swine Health and Production 14(1):35-41.
5. Christopher-Hennings, J., K.S. Faaberg, W.L. Mengeling, M.P. Murtaugh, E.A. Nelson, M.B. Roof, E.M. Vaughn, K.-J. Yoon and J.J. Zimmerman. 2002. PRRS diagnostic: Interpretation and limitations. Swine Health and Production 10:213-218.
6. Christopher-Hennings, J., E.A. Nelson and D.A. Benfield. 1996. Detecting PRRSV in boar semen. Swine Health and Production 4:37-39.
7. Yaeger, M. J., T. Prieve, J. Collins, J. Christopher-Hennings, E. Nelson and D. A. Benfield. 1993. Evidence for the transmission of porcine reproductive and respiratory syndrome (PRRS) virus in boar semen. Swine Health and Production. 1:7-9.
8. Benfield, D. A., L. Harris, E. Nelson, J. Christopher-Hennings, J. Collins, D. Chladek, W. Christianson, R. Morrison, D. Gorycyca. 1992. Properties of SIRS virus isolate ATCC VR-2332 in the United States and preliminary characterization of a monoclonal antibody to this virus. American Association of Swine Practitioners Newsletter 4(4):19-21.
9. Kritchevsky J.E., Stevens D. L., Christopher-(Hennings) J., and Cook W. O., Peritoneal dialysis for presurgical management of ruptured bladder in a foal. 1984. Journal of the American Veterinary Medical Association 185:81-82.

Education

MS 1990: University of Wisconsin-Madison Veterinary Science
DVM 1983: University of Minnesota-St. Paul Veterinary Medicine
BS 1975: University of Wisconsin-Madison Natural Resources