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Eric Nelson

Photo of Eric Nelson
Title Assistant Department Head/Distinguished Professor
Office Building Animal Disease Research & Diagnostic Laboratory
Room Number 123
Mailing Address South Dakota State University
Veterinary & Biomedical Sciences
Animal Disease Research & Diagnostic Laboratory
SAR 123, Box 2175
Brookings, SD 57007

Education

Ph.D., 1993, South Dakota State University, Brookings, SD.
M.A., 1981, University of South Dakota, Vermillion, SD.
B.A., 1979, Mount Marty College, Yankton, SD.

Professional Memberships

American Society for Virology
Conference of Research Workers in Animal Disease
American Association of Veterinary Laboratory Diagnosticians
American Association of Swine Veterinarians

Academic Interests/Expertise

Viral diseases of swine
Diagnostic reagents and assays
Transboundary and emerging diseases

Creative Activities

RECENT PEER REVIEWED PUBLICATIONS

Okda, F., S. Lawson, A. Singrey, J. Nelson, K.S Hain, L.R Joshi, J. Christopher-Hennings, E.A. Nelson, D. G. Diel. 2017. The S2 glycoprotein subunit of porcine epidemic diarrhea virus contains immunodominant neutralizing epitopes. Virology. 509:185-194.

Wang, X., M. Ohnstad, A. Nelsen, E. Nelson. 2017. Porcine Epidemic Diarrhea Virus Does Not Replicate in Porcine Monocyte-derived Dendritic Cells, but Activates the Transcription of Type I interferon and Chemokine. Veterinary Microbiology. 208:77-81.

Van Noort, A., A. Nelson, A.E. Pillatzki, D.G. Diel, F. Li, E. Nelson, X. Wang. 2017. Intranasal immunization of pigs with porcine reproductive and respiratory syndrome virus-like particles plus 2’,3’-cGMP VacciGrade™ adjuvant exacerbates viremia after virus challenge. Virology Journal 14:76.

Joshi, L.R., M.H.V. Fernandes, T. Clement, S. Lawson, A. Pillatzki, T.P Resende, F. Vanucci, G.F. Kutish, E.A. Nelson, D.G. Diel. 2016. Pathogenesis of Senecavirus A infection in finishing pigs. J. Gen. Virol. doi: 10.1099/jgv.0.000631.

Hain, K.S., L.R. Joshi, F. Okda, J. Nelson, A. Singrey, S. Lawson, A. Pillatzki, G.F. Kutish, E.A. Nelson, E.F. Flores, D.G. Diel. 2016. Immunogenicity of a recombinant parapoxvirus expressing the spike protein of porcine epidemic diarrhea virus. J. Gen. Virol. 97:2719-2731. doi: 10.1099/jgv.0.000586.

Vitosh-Sillman, S., J. Loy, B. Brodersen, C. Kelling, A. Doster, C. Topliff, E. Nelson, J. Bai, L. Peddireddi, B. Hause, R. Hesse. 2016. Experimental infection of conventional nursing pigs and their dams with porcine deltacoronavirus. J. Vet. Diagn. Invest. 28:468-497.

Diel, D.G., S. Lawson, F. Okda, A. Singrey, T. Clement, M.H.V. Fernandes, J. Christopher-Hennings, E.A. Nelson. 2016. Porcine epidemic diarrhea virus: an overview of current virological and serological diagnostic methods. Virus Res. doi.org/10.1016/j.virusres. 2016.05.013.

Song, Y., P. Singh, E. Nelson, S. Ramamoorthy. 2016. A computationally-designed serological assay for the porcine epidemic diarrhea virus. J. Clin. Micro. doi:10.1128/JCM.00460-16.

Okda, F., S. Lawson, X. Liu, A. Singrey, T. Clement, J. Nelson, J. Christopher-Hennings, E.A. Nelson. 2016. Development of monoclonal antibodies and serological assays including indirect ELISA and fluorescent microsphere immunoassays for diagnosis of porcine deltacoronavirus. BMC Vet. Res. 12:95. doi: 10.1186/s12917-016-0716-6.

Clement, T., A. Singrey, S. Lawson, F. Okda, J. Nelson, D. Diel, E.A. Nelson, J. Christopher-Hennings. 2016. Quantitation of porcine epidemic diarrhea virus neutralizing antibodies in sow serum, colostrum, milk and piglet serum after feedback. J. Swine Health and Prod. 24:147-153.

Useh, N.M., E.O. Ngbede, N. Akange, M. Thomas, A. Foley, M. Chan Keena, E. Nelson, J. Christopher-Hennings, M. Tomita, H. Suzuki, J. Scaria. 2016. Draft genome sequences of 37 Salmonella enterica strains isolated from poultry sources in Nigeria. Genome Announc. 4(3):e00315-16. doi:10.1128/genomeA.00315-16.

Joshi, L., K. Mohr, T. Clement, K. Hain, B. Myers, J. Yaros, E. Nelson, J. Christopher-Hennings, D. Gava, R. Schaefer, L. Caron, S. Dee, D. Diel. 2016. Detection of the newly emerging Senecavirus A in pigs, mice and houseflies. J. Clin. Micro. 54:1536-1545. doi: 10.1128/JCM.03390-15.

Wang, X., H. Zhang, A.M. Abel, E. Nelson. 2016. Protein kinase R (PKR) plays a pro-viral role in porcine reproductive and respiratory syndrome virus (PRRSV) replication by modulating viral gene transcription. Arch. of Virol. 161:327-333. 10.1007/s00705-015-2671-0.

Swartz, J.E., D.W. Brake, E.E. Grings, E.A. Nelson, C.L. Wright, J.A. Walker, E.J. Blon, G.A. Perry. 2016. Effects of enzymatically hydrolyzed yeast supplementation and supplementation frequency on nitrogen balance and apparent digestibility in periparturient beef cows. J. Animal Science 94(2)169-170.

Dee, S., C. Neill, A. Singrey, T. Clement, R. Cochrane, C. Jones, G. Patterson, J. Christopher-Hennings, E. Nelson. 2016. Modeling the transboundary risk of feed ingredients contaminated with porcine epidemic diarrhea virus. BMC Vet. Res. 12:51.

Sreenivasan, C., M. Thomas, Z. Sheng, B. Hause, E. Collin, D. Knudsen, A. Pillatzki, E. Nelson, D. Wang, R. Kaushik, F. Li. 2015. Replication and transmission of novel bovine influenza D virus in guinea pig model. J. Virol. 89:11990-12001.

Quast, M., C. Sreenivasan, G. Sexton, A. Singrey, L. Fawcett, D. Lauer, S. Voss, S. Pollock, C.W. Cunha, J. Christopher-Hennings, E. Nelson, F. Li. 2015. Serological evidence for the presence of influenza D virus in small ruminants. Vet. Micro. 180(3-4):281-285.

Ran, Z., H. Shen, Y. Lang, E. Kolb, N. Turan, L. Zhu, J. Ma, B. Bawa, Q. Liu, H. Liu, M. Quast, G. Sexton, F. Krammer, B. Hause, J. Christopher-Hennings, E. Nelson, J. Richt, F. Li, and W. Ma. 2015. Domestic pigs are susceptible to infection with influenza B viruses. J. Virol. 89:4818-4826.

Collin, E.A., S. Anbalagan, F. Okda, R. Batman, E.A. Nelson, B.M. Hause. 2015. An inactivated vaccine made from a U.S. field isolate of porcine epidemic disease virus is immunogenic in pigs. BMC Vet. Res. 11:62.

Robinson, S., J. Li, E.A. Nelson, M.P. Murtaugh. 2015. Broadly neutralizing antibodies against the rapidly evolving Porcine reproductive and respiratory syndrome virus. Virus Res. 203:56-65.

Clement, T., G. Kutish, J. Nezworski, J. Scaria, E. Nelson, J. Christopher-Hennings, D. Diel. 2015. Complete genome sequence of a highly pathogenic avian influenza virus (H5N2) associated with an outbreak in commercial chickens, Iowa, USA, 2015. Genome Announc. 3(3):e00613-15. doi:10.1128/genomeA.00613-15.

Okda, F., X. Liu, A. Singrey, T. Clement, J. Nelson, J. Christopher-Hennings, E.A. Nelson, S. Lawson. 2015. Development of an indirect ELISA, blocking ELISA, fluorescent microsphere immunoassay and fluorescent focus neutralization assay for serologic evaluation of exposure to North American strains of Porcine Epidemic Diarrhea Virus. BMC Vet. Res. 11:180. doi:10.1186/s12917-015-0500-z.

Dee, S., C. Neill, T. Clement, A. Singrey, J. Christopher-Hennings, E. Nelson. 2015. An evaluation of porcine epidemic diarrhea virus survival in individual feed ingredients in the presence or absence of a liquid antimicrobial. Porcine Health Management. 1:9 doi:10.1186/s40813-015-0003-0.

Hause, B., E. Collin, R. Liu, B. Huang, Z. Sheng, W. Lu, D. Wang, E. Nelson, F. Li. 2014. Characterization of a novel influenza virus in cattle and swine: Proposal for a new genus in the Orthomyxoviridae family. mBio 5(2):e00031-14. doi:10.1128.

Dee S., C. Neill, T. Clement, J. Christopher-Hennings, E. Nelson. 2014. An evaluation of a liquid antimicrobial (Sal CURB®) for reducing the risk of porcine epidemic diarrhea virus infection of naïve pigs during consumption of contaminated feed. BMC Vet. Res. 10:220.

Dee S., T. Clement, A. Schelkopf, J. Nerem, D. Knudsen, J. Christopher-Hennings, E. Nelson. 2014. An evaluation of contaminated complete feed as a vehicle for porcine epidemic diarrhea virus infection of naïve pigs following consumption via natural feeding behavior: Proof of concept. BMC Vet. Res. 10:176.

Christopher-Hennings J., K. Araujo, Y. Fang, S. Lawson, E. Nelson, J. Lunney. 2013. Considerations for performing Luminex multianalyte profiling (xMAP) in veterinary diagnostic laboratories. J. Vet. Diagn. Invest. 25:773.

Christopher-Hennings J, K.P.C. Araujo, C.J.H. Souza, Y. Fang, S. Lawson, E.A. Nelson, T. Clement, M. Dunn, J.K. Lunney. 2013. Opportunities for bead-based multi-plex assays in veterinary diagnostic laboratories. J. Vet. Diagn. Invest. 25:671-691.

Olsen C., C. Wang, J. Christopher-Hennings, K. Doolittle, K. Harmon, S. Abate, A. Kittawornrat, S. Lizano, R. Main, E. Nelson, T. Otterson, Y. Panyasing, C. Rademacher, R. Rauh, R. Shah, J. Zimmerman. 2013. Probability of detecting porcine reproductive and respiratory syndrome virus infection using pen-based swine oral fluid specimens as a function of within-pen prevalence. J. Vet. Diagn. Invest. 25:328-325.

Zhang, H., X. Guo, E. Nelson, J. Christopher-Hennings, X. Wang. 2012. Porcine reproductive and respiratory syndrome virus activates the transcription of interferon alpha/beta (IFN-α/β) in monocyte-derived dendritic cells (Mo-DC). Vet. Microbiol. 159:494.

Anderson, T., W. Laegreid, F. Cerutti, F. Osorio, E. Nelson, J. Christopher-Hennings, T. Goldberg. 2012. Ranking viruses: Measures of positional importance within networks define core viruses for rational polyvalent vaccine development. Bioinformatics 28:1624-1632.

Lawson, S., Y. Li, J. Patton, R.J. Langenhorst, Z. Sun, Z. Jiang, J. Christopher-Hennings, E.A. Nelson, D. Knudsen, Y. Fang, K.-O. Chang. 2012. Interleukin-1β expression by a recombinant porcine reproductive and respiratory syndrome virus. Virus Res. 163:461-468.

Langohr, I.M., G.W. Stevenson, E.A. Nelson, S.D. Lenz, H., R.M. Pogranichniy. 2012. Experimental co-infection of pigs with bovine viral diarrhea virus 1 and porcine circovirus-2. J. Vet. Diagn. Invest. 24:51-64.

Kittawornrat, A., C. Wang, G. Anderson, A. Ballagi, A. Broes, S. Carman, K. Doolittle, J. Galeota, J. Johnson, S. Lizano, E. Nelson, D. Patnayak, R. Pogranichniy, A. Rice, G. Scherba, J. Zimmerman. 2012. Ring test evaluation for the detection of PRRSV antibodies in oral fluid specimens using a commercial PRRSV serum antibody ELISA. J. Vet. Diagn. Invest. 24:1057-1063.

Langenhorst, R., S. Lawson, A. Kittawornrat, J. Zimmerman, Z. Sun, Y. Li, J. Christopher-Hennings, E. Nelson, Y. Fang. 2012. Development of a fluorescent microsphere immunoassay for detection of antibodies against PRRSV using oral fluid samples as an alternative to serum-based assays. Clin. and Vacc. Immunol. 19:180-189.

Brockmeier, S.L., C.L. Loving, E.A. Nelson, L.C. Miller, T.L. Nicholson, K.M. Register, M.J. Grubman, D.E. Brough, M.E. Kehrli. 2012. Effects of interferon-α on the immune response to porcine reproductive and respiratory syndrome virus. Clin. and Vacc. Immunol. 19:508-514.

Awards & Honors

Distinguished Professor, South Dakota State University, 2017.

Pat and Jo Scott Cannon Intellectual Property Commercialization Award, 2015.

South Dakota State University Gamma Sigma Delta Research Award, 2009.

SDSU Technology Transfer Office Intellectual Property Commercialization Award, 2009.

Joseph J. Garbarino Achievement Award. Presented by the Animal Health Institute Foundation for original research in animal health, 1994.