Eric Nelson

Professional Memberships

American Society for Virology
Conference of Research Workers in Animal Disease
American Association of Veterinary Laboratory Diagnosticians
American Association of Swine Veterinarians
Center for Biologics Research & Commercialization (SD Governor’s Office of Economic Development)

Academic Interests/Expertise

Virology and veterinary diagnostics

Creative Activities

Selected Recent Publications

Dee, S., F. Bauermann, M. Niederwerder, A. Singrey, T. Clement, M. deLima, C. Long, G. Patterson, M. Sheehan, A. Stoian, V. Petrovan, C. Jones, J. de Jong, J. Ji, G. Spronk, J. Hennings, J. Zimmerman, B. Rowland, E. Nelson, P. Sundberg, D. Diel. 2018. Survival of viral pathogens in animal feed ingredients under transboundary shipping models. PloS ONE. doi:10.1371/journal.pone.0194509. March 20, 2018.

Sreenivasan, C.C., S.S. Jandhyala, S. Luo, B.M. Hause, M. Thomas, D.E.B. Knudsen, P. Stein, T. Clement, S. Reedy4, T.M. Chambers, J. Christopher-Hennings, E. Nelson, D. Wang, R.S. Kaushik, F. Li. 2018. Phylogenetic analysis and characterization of a sporadic isolate of equine influenza A H3N8 from an unvaccinated horse in 2015. Viruses. January 11, 2018.

Kraft, J.B., K. Woodard, L. Giménez-Lirola, B. Setness, J. Ju, P. Lasley, E. Nelson, J. Zhang, D. Baum, P. Gauger, R. Main, J. Zimmerman. 2018. Serum and mammary secretion antibody responses in PEDV-immune gilts following PEDV vaccination. Journal of Swine Health and Production. 26:34-40.

Nedland, H., J. Wollman, C. Sreenivasen, M. Quast, A. Singrey, L. Fawcett, J. Christopher-Hennings, E. Nelson, R. Kaushik, D. Wang, F. Li. 2017. Serological evidence for the co-circulation of two lineages of influenza D viruses in equine populations of the Midwest United States. Zoonoses and Public Health. doi: 10.1111/zph.12423.

Okda, F., S. Lawson, A. Singrey, J. Nelson, K.S Hain, L.R Joshi, J. Christopher-Hennings, E.A. Nelson, D. G. Diel. 2017. The S2 glycoprotein subunit of porcine epidemic diarrhea virus contains immunodominant neutralizing epitopes. Virology. 509:185-194.

Wang, X., M. Ohnstad, A. Nelsen, E. Nelson. 2017. Porcine Epidemic Diarrhea Virus Does Not Replicate in Porcine Monocyte-derived Dendritic Cells, but Activates the Transcription of Type I interferon and Chemokine. Veterinary Microbiology. 208:77-81.

Van Noort, A., A. Nelson, A.E. Pillatzki, D.G. Diel, F. Li, E. Nelson, X. Wang. 2017. Intranasal immunization of pigs with porcine reproductive and respiratory syndrome virus-like particles plus 2’,3’-cGMP VacciGrade™ adjuvant exacerbates viremia after virus challenge. Virology Journal 14:76.

Wang, X., E.A. Nelson. 2016. Ultrastructure and morphogenesis of PEDV in PEDV-infected Vero-76 cells. Current Topics in Virology. 13:41-46.

Joshi, L.R., M.H.V. Fernandes, T. Clement, S. Lawson, A. Pillatzki, T.P Resende, F. Vanucci, G.F. Kutish, E.A. Nelson, D.G. Diel. 2016. Pathogenesis of Senecavirus A infection in finishing pigs. J. Gen. Virol. doi: 10.1099/jgv.0.000631.

Hain, K.S., L.R. Joshi, F. Okda, J. Nelson, A. Singrey, S. Lawson, A. Pillatzki, G.F. Kutish, E.A. Nelson, E.F. Flores, D.G. Diel. 2016. Immunogenicity of a recombinant parapoxvirus expressing the spike protein of porcine epidemic diarrhea virus. J. Gen. Virol. 97:2719-2731. doi: 10.1099/jgv.0.000586.

Vitosh-Sillman, S., J. Loy, B. Brodersen, C. Kelling, A. Doster, C. Topliff, E. Nelson, J. Bai, L. Peddireddi, B. Hause, R. Hesse. 2016. Experimental infection of conventional nursing pigs and their dams with porcine deltacoronavirus. J. Vet. Diagn. Invest. 28:468-497.

Diel, D.G., S. Lawson, F. Okda, A. Singrey, T. Clement, M.H.V. Fernandes, J. Christopher-Hennings, E.A. Nelson. 2016. Porcine epidemic diarrhea virus: an overview of current virological and serological diagnostic methods. Virus Res. doi.org/10.1016/j.virusres. 2016.05.013.

Song, Y., P. Singh, E. Nelson, S. Ramamoorthy. 2016. A computationally-designed serological assay for the porcine epidemic diarrhea virus. J. Clin. Micro. 54:2039-2046. doi:10.1128/JCM.00460-16.

Okda, F., S. Lawson, X. Liu, A. Singrey, T. Clement, J. Nelson, J. Christopher-Hennings, E.A. Nelson. 2016. Development of monoclonal antibodies and serological assays including indirect ELISA and fluorescent microsphere immunoassays for diagnosis of porcine deltacoronavirus. BMC Vet. Res. 12:95. doi: 10.1186/s12917-016-0716-6.

Clement, T., A. Singrey, S. Lawson, F. Okda, J. Nelson, D. Diel, E.A. Nelson, J. Christopher-Hennings. 2016. Quantitation of porcine epidemic diarrhea virus neutralizing antibodies in sow serum, colostrum, milk and piglet serum after feedback. J. Swine Health and Prod. 24:147-153.

Useh, N.M., E.O. Ngbede, N. Akange, M. Thomas, A. Foley, M. Chan Keena, E. Nelson, J. Christopher-Hennings, M. Tomita, H. Suzuki, J. Scaria. 2016. Draft genome sequences of 37 Salmonella enterica strains isolated from poultry sources in Nigeria. Genome Announc. 4(3):e00315-16. doi:10.1128/genomeA.00315-16.

Joshi, L., K. Mohr, T. Clement, K. Hain, B. Myers, J. Yaros, E. Nelson, J. Christopher-Hennings, D. Gava, R. Schaefer, L. Caron, S. Dee, D. Diel. 2016. Detection of the newly emerging Senecavirus A in pigs, mice and houseflies. J. Clin. Micro. 54:1536-1545. doi: 10.1128/JCM.03390-15.

Wang, X., H. Zhang, A.M. Abel, E. Nelson. 2016. Protein kinase R (PKR) plays a pro-viral role in porcine reproductive and respiratory syndrome virus (PRRSV) replication by modulating viral gene transcription. Arch. of Virol. 161:327-333. 10.1007/s00705-015-2671-0.

Swartz, J.E., D.W. Brake, E.E. Grings, E.A. Nelson, C.L. Wright, J.A. Walker, E.J. Blon, G.A. Perry. 2016. Effects of enzymatically hydrolyzed yeast supplementation and supplementation frequency on nitrogen balance and apparent digestibility in periparturient beef cows. J. Animal Science 94(2)169-170.

Dee, S., C. Neill, A. Singrey, T. Clement, R. Cochrane, C. Jones, G. Patterson, J. Christopher-Hennings, E. Nelson. 2016. Modeling the transboundary risk of feed ingredients contaminated with porcine epidemic diarrhea virus. BMC Vet. Res. 12:51.

Sreenivasan, C., M. Thomas, Z. Sheng, B. Hause, E. Collin, D. Knudsen, A. Pillatzki, E. Nelson, D. Wang, R. Kaushik, F. Li. 2015. Replication and transmission of novel bovine influenza D virus in guinea pig model. J. Virol. 89:11990-12001.

Quast, M., C. Sreenivasan, G. Sexton, A. Singrey, L. Fawcett, D. Lauer, S. Voss, S. Pollock, C.W. Cunha, J. Christopher-Hennings, E. Nelson, F. Li. 2015. Serological evidence for the presence of influenza D virus in small ruminants. Vet. Micro. 180(3-4):281-285.

Ran, Z., H. Shen, Y. Lang, E. Kolb, N. Turan, L. Zhu, J. Ma, B. Bawa, Q. Liu, H. Liu, M. Quast, G. Sexton, F. Krammer, B. Hause, J. Christopher-Hennings, E. Nelson, J. Richt, F. Li, and W. Ma. 2015. Domestic pigs are susceptible to infection with influenza B viruses. J. Virol. 89:4818-4826.

Collin, E.A., S. Anbalagan, F. Okda, R. Batman, E.A. Nelson, B.M. Hause. 2015. An inactivated vaccine made from a U.S. field isolate of porcine epidemic disease virus is immunogenic in pigs. BMC Vet. Res. 11:62.

Robinson, S., J. Li, E.A. Nelson, M.P. Murtaugh. 2015. Broadly neutralizing antibodies against the rapidly evolving Porcine reproductive and respiratory syndrome virus. Virus Res. 203:56-65.

Clement, T., G. Kutish, J. Nezworski, J. Scaria, E. Nelson, J. Christopher-Hennings, D. Diel. 2015. Complete genome sequence of a highly pathogenic avian influenza virus (H5N2) associated with an outbreak in commercial chickens, Iowa, USA, 2015. Genome Announc. 3(3):e00613-15. doi:10.1128/genomeA.00613-15.

Okda, F., X. Liu, A. Singrey, T. Clement, J. Nelson, J. Christopher-Hennings, E.A. Nelson, S. Lawson. 2015. Development of an indirect ELISA, blocking ELISA, fluorescent microsphere immunoassay and fluorescent focus neutralization assay for serologic evaluation of exposure to North American strains of Porcine Epidemic Diarrhea Virus. BMC Vet. Res. 11:180. doi:10.1186/s12917-015-0500-z.

Dee, S., C. Neill, T. Clement, A. Singrey, J. Christopher-Hennings, E. Nelson. 2015. An evaluation of porcine epidemic diarrhea virus survival in individual feed ingredients in the presence or absence of a liquid antimicrobial. Porcine Health Management. 1:9 doi:10.1186/s40813-015-0003-0.

Awards & Honors

University Distinguished Professor, South Dakota State University, 2017.

Pat and Jo Scott Cannon Intellectual Property Commercialization Award, 2015.

South Dakota State University Gamma Sigma Delta Research Award, 2009.

SDSU Technology Transfer Office Intellectual Property Commercialization Award, 2009.

Joseph J. Garbarino Achievement Award. Presented by the Animal Health Institute Foundation for original research in animal health, 1994.

Education

Ph.D., 1993, Biological Sciences/Veterinary Microbiology, South Dakota State University, Brookings, SD.
M.A., 1981, Zoology, University of South Dakota, Vermillion, SD.
B.A., 1979, Chemistry/Biology, Mount Marty College, Yankton, SD.