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Chun-Ming Lin



Assistant Professor, Veterinary Pathologist

Office Building

Animal Disease Research & Diagnostic Laboratory



Mailing Address

Animal Disease Research 1123
Animal Disease Reserch-Box 2175
University Station
Brookings, SD 57007


Dr. Chun-Ming (Jimmy) Lin is our veterinary pathologist and assistant professor with abundant experience in diagnostic and investigative pathology in companion and food animals. His primary research interests focus on the immunopathogenesis of swine viral diseases, especially porcine circovirus, parvovirus, and coronavirus. He also has abundant experience in the development of new diagnostic assays and vaccines.
Dr. Lin grew up in Taiwan, where swine production is one of the most important industries. After he graduated from the veterinary school at National Taiwan University, he stayed an additional 8 years in graduate school to study pathology, immunology, biotechnology, and biostatistics. He then worked as a post-doctoral researcher at the food animal health research program at The Ohio State University and served as an anatomic pathology resident at Cummings School of Veterinary Medicine at Tufts University. He is now eligible for the ACVP certification examination (2020, canceled due to COVID-19).
After work, Jimmy enjoys biking, gardening, and camping. Jimmy met her wife while they were working on a project of food safety in the vet school. They now have a little boy and a dog named Cedar.
Please contact Dr. Lin at 605-688-5679 or


Veterinary Anatomic Pathology Residency, 2017-2020
Section of Anatomic Pathology, Department of Biomedical Sciences
Cummings School of Veterinary Medicine, Tufts University
Postdoctoral Researcher, 2013-2017
Food Animal Health Research Program, Ohio Agriculture and Research Development Center (OARDC), The Ohio State University (OSU)
Advisors: Drs. Linda Saif and Qiuhong Wang
Doctor of Philosophy, 2006-2012
Graduate Institute of Veterinary Medicine, School of Veterinary Medicine, National Taiwan
University (NTU), Taiwan
Thesis: Characterization of porcine circovirus type 2 infection in immune cells and lymphoid
organs by using in vitro and in vivo models;
Advisors: Drs. Victor Fei Pang and Chian-Ren Jeng
Certified Teaching Associate (Bio-statistic) 2011.9-2012.7
Statistics Education Center, NTU
Training Program of Biotechnology, 2005-2012
Center for Biotechnology, NTU
Anatomic Pathology Residency (Combined with MS/PhD program) 2004-2009
School of Veterinary Medicine, National Taiwan University
Master of Veterinary Medicine, 2004-2006
Graduate Institute of Veterinary Medicine, School of Veterinary Medicine, NTU, Taiwan
Bachelor of Veterinary Medicine (DVM equivalent), 1999-2004
Department of Veterinary Medicine, College of Bio-Resources and Agriculture, NTU, Taiwan

Awards and Honors

The Presidential Award NTU, 2002
Doctor's Award for Academic Research Thesis, College of Bioresources and Agriculture, NTU, 2008
Grantee of Postdoctoral Research Abroad Program, National Science Council, Taiwan, 2013
OARDC Professional Growth Scholarship, OARDC, OSU, 2014

Professional Memberships

American College of Veterinary Pathologist Board, Phase I Examination (2019); Phase II eligible (2020)
Taiwanese National Board-certified Veterinarian
National Civil Service Exam (Veterinarian)
No. 5190, Council of Agriculture, Taiwan, since 2004.08

Area(s) of Research

Selected Publications
1. Porcine Epidemic Diarrhea Virus
1. Lin C.M.*, Ghimire S.*, Hou Y., Boley P., Langel, S.N., Vlasova, A.N., Saif, L.J., Wang, Q. 2019. Pathogenicity and immunogenicity of attenuated porcine epidemic diarrhea virus PC22A strain in conventional weaned pigs. BMC Vet Res 15:26 (* Co-first author paper)
2. Lin C.M., Hou Y., Marthaler, D., Gao, X., Liu, X., Zheng, L., Saif, L.J., and Wang, Q. 2017. Generation of attenuated US PEDV vaccine candidates via continuous cell culture passages. Vet Microbiol. 201:62-71.
3. Lin C.M., Saif L.J., Marthaler, D., and Wang, Q. 2016. Evolution, antigenicity and pathogenicity of global porcine epidemic diarrhea virus strains (Review article). Special Issue - Re-emerging Porcine Coronaviruses, Virus Research 226:20-39.
4. Lin C.M., Annamalai T., Liu X., Gao X., Lu Z., El-Tholoth M., Hu H., Saif L.J., Wang Q. 2015. Experimental infection of a U.S. spike-insertion deletion porcine epidemic diarrhea virus in conventional nursing piglets and cross-protection to the original US PEDV infection. Vet Res. 20:134.
5. Liu X.*, Lin C.M.*, Annamalai T., Gao X., Lu Z., Esseili M.A., Jung K., El-Tholoth M., Saif L.J., Wang Q. 2015. Determination of the infectious titer and virulence of an original U.S. porcine epidemic diarrhea virus PC22A strain. Vet Res. 46:109. (* Co-first author paper)
6. Lin C.M., Gao X., Oka T., Vlasova A.N., Esseili M.A., Wang Q., Saif L.J. 2015. Antigenic relationships among porcine epidemic diarrhea virus and transmissible gastroenteritis virus strains. J Virol. 89:3332-3342.
B. Porcine Circovirus Type 2
1. Lin, C.M., Jeng, C.R., Liu, J.P., Lin, E.C., Chang, C.C., Huang, Y.L., Tsai, Y.C., Chia, M.Y., Wan, C.H., Pang, V.F. 2013. Immune gene expression profiles in swine inguinal lymph nodes with different viral loads of porcine circovirus type 2. Vet Microbiol. 162:519-529.
2. Lin, C.M., Jeng, C.R., Hsiao, S.H., Lee, Y., Tsai, Y.C., Chia, M.Y., Pang, V.F. 2012. Monocyte-derived dendritic cells enhance cell proliferation and porcine circovirus type 2 replication in concanavalin A-stimulated swine peripheral blood lymphocytes in vitro. Vet Immunol Immunopathol. 145:368-78.
3. Lin, C.M., Jeng, C.R., Hsiao, S.H., Liu, J.P., Chang, C.C., Chiou M.T., Tsai, Y.C., Chia, M.Y., Pang, V. F. 2011. Immunopathological characterization of porcine circovirus type 2 infection-associated follicular changes in inguinal lymph nodes using high-throughput tissue microarray Vet. Microbiol. 149:72-84.
4. Lin, C.M., Jeng, C.R., Hsiao, S.H., Chang, C.C., Liu, C.H., Tsai, Y.C., Chia, M.Y., and Pang, V. F. 2009. Development and evaluation of an indirect in situ polymerase chain reaction for the detection of porcine circovirus type 2 in formalin-fixed and paraffin-embedded tissue specimens. Vet. Microbiol. 138:225-234.
5. Lin, C.M., Jeng, C.R., Chang, H.W., Guo, I.C., Huang, Y.L., Tsai, Y.C., Chia, M.Y., and Pang, V. F. 2008. Characterization of porcine circovirus type 2 (PCV2) infection in swine lymphocytes using mitogen-stimulated peripheral blood lymphocytes from healthy PCV2-carrier pigs. Vet. Immunol. Immunopathol. 124:355-366.
C. Porcine Torque Teno Sus Virus
1. Lee Y., Lin C.M., Jeng C.R., Chang H.W., Chang C.C., Pang V.F. 2015. The pathogenic role of torque teno sus virus 1 and 2 and their correlations with various viral pathogens and host immunocytes in wasting pigs. Vet Microbiol.180:186-95.
D. Porcine Reproductive and Respiratory Syndrome Virus
1. Chia, M.Y., Hsiao, S.H., Chan, H.T., Do, Y.Y., Huang, P.L., Chang, H.W., Tsai, Y.C., Lin, C.M., Pang, V. F., and Jeng, C.R. 2011. Evaluation of the immunogenicity of a transgenic tobacco plant expressing the recombinant fusion protein of GP5 of porcine reproductive and respiratory syndrome virus and B subunit of Escherichia coli heat-labile enterotoxin in pigs. Vet. Immunol. Immunopathol. 140:215-225.
2. Chia, M.Y., Hsiao, S.H., Chan, H.T., Do, Y.Y., Huang, P.L., Chang, H.W., Tsai, Y.C., Lin, C.M., Pang, V. F., and Jeng, C.R. 2010. The immunogenicity of DNA constructs co-expressing GP5 and M proteins of porcine reproductive and respiratory syndrome virus conjugated by GPGP linker in pigs. Vet. Microbiol. 146:189-199.
E. Other Pathogens
1. Lee, F., Chen, J.L., Lin, C.M., Wang, F.I. 2011. Presence of bluetongue virus in the marginal zone of the spleen in acute infected sheep. Vet Microbiol. 152:96-100.
2. Tsai, H.J., Huang, H.C., Lin, C.M., Lien, Y.Y., Chou, C.H. 2007. Salmonellae and campylobacters in household and stray dogs in northern Taiwan. Vet Res Commun. 31:931-9.