Dr. Xiuqing Wang’s lab is primarily focused on viral pathogenesis, viral immunity, and vaccine development. The main research topic
areas include the better understanding of the innate immunity against porcine reproductive and respiratory syndrome virus (PRRSV) and porcine epidemic diarrhea virus (PEDV) and innovative approaches for novel vaccine development against these devastating diseases affecting the swine industry. We primarily employ primary monocytederived dendritic cells as an in vitro model system to study virus-host interaction and innate immunity.
We are particularly interested in the role of type I interferon and interferon induced
genes such as protein kinase R (PKR) in virus replication. We are also assessing the feasibility of using virus-like particles
generated from the Baculovirus expression system as potential vaccine candidates for PRRSV and PEDV.